C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: junctional adhesion molecule 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166086 JAM3 9606 + 11:134068925-134152001 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000299106 JAM3-001 134068925-134152001 protein_coding
  ENST00000441717 JAM3-002 134069071-134151751 protein_coding
  ENST00000524969 JAM3-006 134126339-134144996 processed_transcript
  ENST00000531302 JAM3-008 134069085-134145431 retained_intron
  ENST00000532165 JAM3-007 134139640-134145012 processed_transcript
  ENST00000532252 JAM3-004 134069071-134144826 nonsense_mediated_decay
  ENST00000533711 JAM3-010 134147798-134149208 retained_intron
  ENST00000534549 JAM3-005 134069071-134144934 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000299106ENST00000441717
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000299106 N/A N/A 10.955±0.00 3.697±0.00 5.018±0.00 3.309±0.00 N/A 25.327±0.00 6.550±2.02 0.542±0.00 11.309±8.65 23.753±14.71 21.852±11.09
ENST00000441717 15.058±0.00 13.295±0.00 28.310±0.00 6.393±0.98 28.985±0.00 6.254±0.00 6.586±0.00 N/A 19.850±0.00 3.707±0.00 8.733±0.00 N/A 29.252±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004R4 CIL_0004R4_0003 CGP 11:133908564-134152001

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IDA angiogenesis
GO:0001780 IEA neutrophil homeostasis
GO:0002250 IEA adaptive immune response
GO:0002318 IEA myeloid progenitor cell differentiation
GO:0002523 IEA leukocyte migration involved in inflammatory response
GO:0005178 IPI integrin binding
GO:0005515 IPI:IEA protein binding
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005923 IEA tight junction
GO:0007160 IEA cell-matrix adhesion
GO:0007283 IEA spermatogenesis
GO:0007286 IEA spermatid development
GO:0007596 TAS blood coagulation
GO:0016021 IEA integral component of membrane
GO:0016477 IEA cell migration
GO:0019226 IEA transmission of nerve impulse
GO:0030010 IEA establishment of cell polarity
GO:0030057 IDA desmosome
GO:0030198 TAS extracellular matrix organization
GO:0031103 IEA axon regeneration
GO:0033010 IEA paranodal junction
GO:0042552 IEA myelination
GO:0042803 IEA protein homodimerization activity
GO:0043220 IEA Schmidt-Lanterman incisure
GO:0044291 IDA cell-cell contact zone
GO:0046982 IEA protein heterodimerization activity
GO:0050900 TAS leukocyte migration
GO:0090022 IDA regulation of neutrophil chemotaxis
GO:0090138 IEA regulation of actin cytoskeleton organization by cell-cell adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061794 jam3b junctional adhesion molecule 3b protein_coding Danio_rerio
ENSDARG00000086037 jam3a junctional adhesion molecule 3a protein_coding Danio_rerio
ENSMUSG00000031990 Jam3 junction adhesion molecule 3 protein_coding Mus_musculus

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