C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement component 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166278 C2 9606 + 6:31897785-31945672 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000299367 C2-001 31927477-31945672 protein_coding
  ENST00000383177 C2-003 31927763-31945624 protein_coding
  ENST00000411571 C2-006 31919941-31937459 nonsense_mediated_decay
  ENST00000413154 C2-007 31919984-31928894 protein_coding
  ENST00000418949 C2-002 31927703-31935058 protein_coding
  ENST00000442278 C2-010 31927496-31945671 protein_coding
  ENST00000447952 C2-009 31927525-31934245 protein_coding
  ENST00000452202 C2-015 31901004-31934295 protein_coding
  ENST00000452323 C2-014 31900999-31945671 protein_coding
  ENST00000468407 C2-013 31943673-31945672 processed_transcript
  ENST00000469372 C2-017 31897785-31945521 protein_coding
  ENST00000482060 C2-018 31927739-31945391 nonsense_mediated_decay
  ENST00000484636 C2-008 31920096-31935990 nonsense_mediated_decay
  ENST00000485690 C2-012 31934283-31943758 nonsense_mediated_decay
  ENST00000486124 C2-005 31936055-31945672 retained_intron
  ENST00000494905 C2-011 31932348-31934282 protein_coding
  ENST00000497706 C2-004 31897787-31944853 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonLungOvaryPlacentaENST00000299367ENST00000383177ENST00000411571ENST00000442278ENST00000469372ENST00000482060ENST00000497706
Transcript ID Adipose Brain Breast Colon Lung Ovary Placenta
ENST00000299367 N/A N/A N/A N/A N/A 8.529±1.35 25.039±11.81
ENST00000383177 12.140±0.00 N/A 14.269±0.00 5.306±0.00 N/A N/A 18.601±0.00
ENST00000411571 N/A N/A N/A N/A N/A 11.183±0.00 N/A
ENST00000442278 N/A N/A N/A N/A 3.188±0.00 13.649±8.91 12.625±0.00
ENST00000469372 N/A N/A N/A N/A N/A N/A 16.640±0.00
ENST00000482060 5.748±0.00 0.930±0.00 N/A N/A 10.692±7.45 N/A N/A
ENST00000497706 N/A N/A N/A N/A 4.105±0.00 21.046±0.00 11.118±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000421 CIL_000421_0001 CGP 6:31897785-31945672

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 TAS extracellular space
GO:0006508 IEA proteolysis
GO:0006956 IMP:IEA complement activation
GO:0006958 IEA complement activation, classical pathway
GO:0007584 IEA response to nutrient
GO:0030449 TAS regulation of complement activation
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0070062 IDA extracellular vesicular exosome
GO:2000427 IMP positive regulation of apoptotic cell clearance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019772 complement component 2 protein_coding Danio_rerio
ENSMUSG00000024371 C2 complement component 2 (within H-2S) protein_coding Mus_musculus

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