C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serpin peptidase inhibitor, clade B (ovalbumin), member 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166396 SERPINB7 9606 + 18:63752935-63805376 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336429 SERPINB7-201 63753047-63805376 protein_coding
  ENST00000398019 SERPINB7-001 63775410-63805370 protein_coding
  ENST00000425392 SERPINB7-002 63752935-63796312 protein_coding
  ENST00000431370 SERPINB7-005 63777977-63796313 protein_coding
  ENST00000447428 SERPINB7-004 63777777-63798643 protein_coding
  ENST00000540675 SERPINB7-202 63775375-63805376 protein_coding
  ENST00000546027 SERPINB7-203 63777777-63805376 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000336429ENST00000398019ENST00000425392ENST00000447428ENST00000546027
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000336429 N/A N/A N/A N/A N/A N/A 0.017±0.00 0.573±0.00 N/A 0.007±0.00 N/A N/A
ENST00000398019 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.990±0.00 0.178±0.00
ENST00000425392 N/A N/A N/A N/A N/A 0.068±0.00 N/A N/A N/A N/A N/A N/A
ENST00000447428 N/A N/A N/A 0.248±0.00 N/A N/A N/A N/A 0.140±0.00 0.293±0.00 0.293±0.00 N/A
ENST00000546027 0.050±0.00 0.115±0.00 0.093±0.00 0.026±0.00 0.059±0.00 N/A 0.068±0.00 N/A N/A 0.074±0.02 1.625±1.02 0.057±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000160 CIL_000160_000A CGP 18:63647579-63805376
CIL_000160 CIL_000160_0005 CGP 18:63752935-63903890

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0032914 IEA positive regulation of transforming growth factor beta1 production
GO:0032967 IEA positive regulation of collagen biosynthetic process
GO:0072126 IEA positive regulation of glomerular mesangial cell proliferation
GO:0090362 IEA positive regulation of platelet-derived growth factor production

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014556 serpinb1l3 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3 protein_coding Danio_rerio
ENSDARG00000057263 zgc:173729 zgc:173729 protein_coding Danio_rerio
ENSDARG00000091801 si:ch73-303g23.4 si:ch73-303g23.4 protein_coding Danio_rerio
ENSDARG00000095830 serpinb1l1 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1 protein_coding Danio_rerio
ENSDARG00000096888 serpinb1l4 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4 protein_coding Danio_rerio
ENSMUSG00000067001 Serpinb7 serine (or cysteine) peptidase inhibitor, clade B, member 7 protein_coding Mus_musculus

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