C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: isocitrate dehydrogenase 3 (NAD+) alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166411 IDH3A 9606 + 15:78131498-78171949 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000299518 IDH3A-001 78149321-78171949 protein_coding
  ENST00000557826 IDH3A-016 78149362-78160206 protein_coding
  ENST00000557960 IDH3A-020 78166241-78171255 nonsense_mediated_decay
  ENST00000558016 IDH3A-019 78166105-78169258 retained_intron
  ENST00000558509 IDH3A-009 78149377-78163563 nonsense_mediated_decay
  ENST00000558535 IDH3A-002 78159970-78170542 processed_transcript
  ENST00000558554 IDH3A-006 78149360-78169560 protein_coding
  ENST00000558602 IDH3A-003 78156923-78169671 retained_intron
  ENST00000558605 IDH3A-007 78131498-78157579 processed_transcript
  ENST00000558933 IDH3A-008 78149326-78166200 nonsense_mediated_decay
  ENST00000559106 IDH3A-011 78149409-78161633 nonsense_mediated_decay
  ENST00000559186 IDH3A-012 78149368-78161768 protein_coding
  ENST00000559205 IDH3A-017 78149380-78169283 protein_coding
  ENST00000559803 IDH3A-021 78149380-78168966 nonsense_mediated_decay
  ENST00000559865 IDH3A-010 78149377-78161692 nonsense_mediated_decay
  ENST00000559881 IDH3A-014 78149377-78162310 protein_coding
  ENST00000559889 IDH3A-004 78149378-78169674 retained_intron
  ENST00000560396 IDH3A-023 78149373-78161768 nonsense_mediated_decay
  ENST00000560414 IDH3A-013 78149392-78155732 retained_intron
  ENST00000560667 IDH3A-005 78149360-78169715 nonsense_mediated_decay
  ENST00000560770 IDH3A-015 78149377-78157631 protein_coding
  ENST00000561279 IDH3A-022 78149362-78162367 protein_coding
  ENST00000561366 IDH3A-018 78163716-78166473 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000558016ENST00000558535ENST00000558554ENST00000558933ENST00000559803ENST00000559881ENST00000560414ENST00000560667
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000558016 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 25.263±0.00 17.274±0.00 52.523±0.00
ENST00000558535 N/A N/A 2.431±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000558554 N/A N/A N/A N/A N/A N/A 4.383±0.00 N/A N/A N/A 2.542±0.00 N/A N/A N/A
ENST00000558933 N/A N/A N/A N/A N/A 9.170±0.00 N/A N/A 3.627±0.00 3.385±0.00 N/A 4.608±0.00 11.933±3.03 N/A
ENST00000559803 17.749±0.00 17.982±0.00 N/A 33.038±14.98 11.673±8.41 14.143±6.36 36.050±28.99 16.166±12.37 5.440±2.78 11.660±5.52 29.404±0.00 11.239±6.41 14.668±0.00 29.879±2.87
ENST00000559881 N/A N/A N/A N/A N/A N/A N/A 1.737±0.00 5.029±0.00 N/A 7.211±0.00 N/A N/A N/A
ENST00000560414 N/A N/A N/A N/A N/A N/A N/A 2.839±0.00 N/A N/A N/A N/A N/A N/A
ENST00000560667 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.683±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001UM CIL_0001UM_0001 CGP 15:78104606-78171949
CIL_0003NR CIL_0003NR_0002 CGP 15:78131498-78245688

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004449 IEA isocitrate dehydrogenase (NAD+) activity
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0005975 NAS carbohydrate metabolic process
GO:0006099 TAS:IEA tricarboxylic acid cycle
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030278 idh3a isocitrate dehydrogenase 3 (NAD+) alpha protein_coding Danio_rerio
ENSMUSG00000032279 Idh3a isocitrate dehydrogenase 3 (NAD+) alpha protein_coding Mus_musculus

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