C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: WEE1 G2 checkpoint kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166483 WEE1 9606 + 11:9573681-9593457 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000299613 WEE1-002 9574687-9589984 protein_coding
  ENST00000450114 WEE1-001 9573681-9589207 protein_coding
  ENST00000524549 WEE1-003 9575490-9581487 retained_intron
  ENST00000524612 WEE1-004 9577785-9586581 protein_coding
  ENST00000527848 WEE1-008 9586714-9593457 protein_coding
  ENST00000530175 WEE1-007 9581544-9588701 nonsense_mediated_decay
  ENST00000530712 WEE1-005 9581227-9588487 protein_coding
  ENST00000532275 WEE1-006 9585183-9588456 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000299613ENST00000450114ENST00000524549ENST00000524612ENST00000530175ENST00000530712
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000299613 0.809±0.00 N/A 1.101±0.00 0.457±0.00 2.166±0.00 0.984±0.00 N/A 1.032±0.00 N/A N/A N/A 7.188±4.01 7.468±0.00 4.307±0.05
ENST00000450114 4.275±0.00 2.788±0.00 N/A 0.582±0.00 2.269±0.63 2.038±0.00 6.341±4.86 1.330±0.12 2.706±0.00 3.421±0.00 1.796±0.56 9.645±6.79 12.844±3.62 15.657±5.35
ENST00000524549 N/A N/A 1.705±0.00 0.053±0.00 2.677±0.00 1.021±0.00 0.400±0.00 0.440±0.00 2.142±0.00 1.157±0.00 0.101±0.00 2.860±1.34 N/A N/A
ENST00000524612 N/A N/A N/A 0.142±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000530175 N/A N/A N/A 0.613±0.41 N/A 5.421±0.00 1.648±0.00 3.203±0.00 N/A N/A N/A 12.226±0.00 N/A N/A
ENST00000530712 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.106±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009CP CIL_0009CP_0001 VISTA 11:9311967-9915183
CIL_00070N CIL_00070N_0001 CGP 11:9460319-9593457
CIL_0004J5 CIL_0004J5_0001 CGP 11:9573681-9752991

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000226 IEA microtubule cytoskeleton organization
GO:0000278 TAS mitotic cell cycle
GO:0000287 IEA magnesium ion binding
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 TAS:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0007067 IEA mitotic nuclear division
GO:0007596 TAS blood coagulation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030010 IEA establishment of cell polarity
GO:0048812 IEA neuron projection morphogenesis
GO:0051726 TAS regulation of cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000031016 Wee1 WEE 1 homolog 1 (S. pombe) protein_coding Mus_musculus

Loading