C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: alpha-2-macroglobulin-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166535 A2ML1 9606 + 12:8822472-8887001 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000299698 A2ML1-001 8822472-8876785 protein_coding
  ENST00000536789 A2ML1-008 8844954-8846124 protein_coding
  ENST00000537475 A2ML1-006 8867943-8887001 nonsense_mediated_decay
  ENST00000537546 A2ML1-011 8823513-8834935 retained_intron
  ENST00000539547 A2ML1-004 8845004-8876456 protein_coding
  ENST00000540049 A2ML1-010 8845283-8848795 processed_transcript
  ENST00000541459 A2ML1-003 8843236-8875814 protein_coding
  ENST00000545692 A2ML1-009 8845281-8848901 protein_coding
  ENST00000545850 A2ML1-007 8857235-8857864 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000299698ENST00000537475ENST00000539547ENST00000541459
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000299698 0.129±0.00 0.031±0.00 N/A N/A 0.040±0.00 0.017±0.01 N/A 0.035±0.01 0.188±0.00 0.027±0.00 N/A 5.132±5.35 1.105±0.89 0.370±0.00
ENST00000537475 N/A 0.127±0.00 N/A N/A 0.043±0.00 N/A 0.027±0.00 0.175±0.00 N/A N/A 0.010±0.00 N/A N/A N/A
ENST00000539547 N/A N/A N/A N/A N/A N/A N/A 0.323±0.00 N/A N/A N/A 3.682±0.00 0.319±0.00 1.709±0.00
ENST00000541459 0.088±0.00 N/A 0.018±0.00 0.366±0.28 0.146±0.00 0.021±0.00 0.055±0.00 0.127±0.00 0.017±0.00 0.165±0.00 N/A N/A N/A 0.419±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HL CIL_0008HL_0001 VISTA 12:8543390-9149656

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004866 IEA endopeptidase inhibitor activity
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005576 IEA extracellular region
GO:0005615 IEA:IDA extracellular space
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0030414 IDA peptidase inhibitor activity
GO:0052548 IDA regulation of endopeptidase activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008835 A2ML1 (1 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000041645 A2ML1 (2 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000041685 A2ML1 (3 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000056314 a2ml alpha-2-macroglobulin-like protein_coding Danio_rerio
ENSDARG00000074764 A2ML1 (5 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000075737 A2ML1 (6 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000076366 A2ML1 (7 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000076771 A2ML1 (8 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000077171 A2ML1 (9 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000078183 A2ML1 (10 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000078757 A2ML1 (11 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000093199 A2ML1 (12 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio

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