C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caseinolytic mitochondrial matrix peptidase chaperone subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166855 CLPX 9606 - 15:65148219-65185342 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300107 CLPX-001 65148219-65185342 protein_coding
  ENST00000558103 CLPX-006 65158191-65162647 retained_intron
  ENST00000558958 CLPX-002 65156686-65185342 retained_intron
  ENST00000559152 CLPX-003 65150514-65185216 nonsense_mediated_decay
  ENST00000559218 CLPX-005 65166651-65184484 protein_coding
  ENST00000560166 CLPX-007 65154679-65155851 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000300107ENST00000558958ENST00000559152ENST00000560166
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000300107 3.607±0.00 4.565±0.00 0.907±0.00 4.450±0.99 4.785±0.00 2.893±0.88 4.676±1.50 5.599±0.70 5.580±3.10 1.925±0.48 5.018±3.18 6.081±1.44 4.212±0.83 5.271±0.02
ENST00000558958 N/A N/A N/A N/A N/A 2.856±0.00 N/A 4.081±0.00 N/A N/A N/A 5.815±2.31 N/A N/A
ENST00000559152 3.754±0.00 6.918±0.00 1.301±0.00 6.046±0.00 3.698±1.64 2.168±0.00 6.654±0.00 4.055±0.28 3.764±2.69 4.438±0.92 3.981±2.70 8.280±7.03 4.597±3.80 18.052±4.55
ENST00000560166 N/A N/A N/A N/A 6.309±0.00 18.254±0.00 5.938±0.00 15.223±0.00 13.777±0.00 7.486±0.00 6.398±0.00 17.089±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RY CIL_0007RY_0001 VISTA 15:64785331-65389080
CIL_0006TY CIL_0006TY_0002 CGP 15:65117379-65185342

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004176 IDA ATP-dependent peptidase activity
GO:0005515 IPI protein binding
GO:0005524 ISS:IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005743 ISS mitochondrial inner membrane
GO:0005759 IDA mitochondrial matrix
GO:0006200 IDA ATP catabolic process
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006457 IEA protein folding
GO:0008134 IEA transcription factor binding
GO:0009368 IDA endopeptidase Clp complex
GO:0009841 IDA mitochondrial endopeptidase Clp complex
GO:0010952 IDA positive regulation of peptidase activity
GO:0016504 IDA peptidase activator activity
GO:0016887 ISS:IEA ATPase activity
GO:0042645 IDA mitochondrial nucleoid
GO:0046872 IEA metal ion binding
GO:0051082 IEA unfolded protein binding
GO:0051603 IDA proteolysis involved in cellular protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029063 clpxa ClpX caseinolytic peptidase X homolog a protein_coding Danio_rerio
ENSDARG00000067796 clpxb caseinolytic peptidase X homolog b protein_coding Danio_rerio
ENSDARG00000086455 CLPX (3 of 3) caseinolytic mitochondrial matrix peptidase chaperone subunit protein_coding Danio_rerio
ENSMUSG00000015357 Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit protein_coding Mus_musculus

Loading