C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CD3d molecule, delta (CD3-TCR complex)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167286 CD3D 9606 - 11:118338954-118342744 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300692 CD3D-001 118338954-118342744 protein_coding
  ENST00000392884 CD3D-003 118339094-118342631 protein_coding
  ENST00000526561 CD3D-004 118339094-118342631 retained_intron
  ENST00000529594 CD3D-002 118339077-118342647 protein_coding
  ENST00000534687 CD3D-005 118339076-118340937 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000300692ENST00000392884ENST00000526561ENST00000529594ENST00000534687
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000300692 0.132±0.00 10.901±0.00 N/A 0.117±0.00 1.355±0.15 2.872±2.06 0.070±0.00 0.249±0.00 0.889±0.59 4.842±0.44 N/A 1.931±0.96 0.719±0.00 0.448±0.00
ENST00000392884 0.107±0.00 13.047±0.00 N/A N/A 2.971±2.46 2.022±0.00 0.718±0.00 2.084±1.64 1.248±0.83 6.323±0.72 0.155±0.00 0.948±0.00 0.758±0.54 0.509±0.00
ENST00000526561 N/A N/A N/A N/A N/A 1.028±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000529594 N/A 17.991±0.00 N/A 0.208±0.00 N/A N/A N/A 2.367±0.00 0.668±0.00 3.093±0.00 N/A N/A N/A N/A
ENST00000534687 N/A N/A 0.249±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.878±0.00 N/A 0.212±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081E CIL_00081E_0001 VISTA 11:118137591-118740525

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003713 IDA transcription coactivator activity
GO:0004888 IC:IEA transmembrane signaling receptor activity
GO:0005515 IEA protein binding
GO:0005737 NAS cytoplasm
GO:0005886 TAS plasma membrane
GO:0007166 IC:IEA cell surface receptor signaling pathway
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030217 IDA T cell differentiation
GO:0031295 TAS T cell costimulation
GO:0042101 IDA T cell receptor complex
GO:0042105 IEA alpha-beta T cell receptor complex
GO:0045059 ISS positive thymic T cell selection
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0050776 TAS regulation of immune response
GO:0050852 TAS T cell receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000032094 Cd3d CD3 antigen, delta polypeptide protein_coding Mus_musculus

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