C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acetyl-CoA acyltransferase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167315 ACAA2 9606 - 18:49782167-49813960 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000285093 ACAA2-001 49782167-49813960 protein_coding
  ENST00000585948 ACAA2-005 49795776-49811531 protein_coding
  ENST00000586100 ACAA2-004 49795811-49813953 protein_coding
  ENST00000586485 ACAA2-006 49794320-49813937 protein_coding
  ENST00000587994 ACAA2-003 49783505-49813953 protein_coding
  ENST00000589432 ACAA2-007 49783503-49813042 protein_coding
  ENST00000591171 ACAA2-002 49783505-49786619 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000285093ENST00000587994
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000285093 N/A 1.745±0.00 N/A 1.515±0.42 4.699±0.00 N/A 6.167±3.51 N/A N/A N/A 1.325±0.38 3.112±0.97 2.011±0.29 2.467±0.00
ENST00000587994 44.422±0.00 19.465±0.00 14.487±0.00 8.604±5.46 31.737±25.77 34.988±0.00 43.728±38.20 82.728±0.75 128.514±123.65 9.140±4.50 7.577±4.54 33.718±29.48 13.836±1.85 23.340±3.56

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0003988 NAS acetyl-CoA C-acyltransferase activity
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0006631 IEA fatty acid metabolic process
GO:0006695 NAS cholesterol biosynthetic process
GO:0008152 IEA metabolic process
GO:0016747 IEA transferase activity, transferring acyl groups other than amino-acyl groups
GO:0044822 IDA poly(A) RNA binding
GO:0070062 IDA extracellular vesicular exosome
GO:0071456 IDA cellular response to hypoxia
GO:1901029 IDA negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1902109 IDA negative regulation of mitochondrial membrane permeability involved in apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038881 acaa2 acetyl-CoA acyltransferase 2 protein_coding Danio_rerio
ENSMUSG00000036880 Acaa2 acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) protein_coding Mus_musculus

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