C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium channel, voltage-dependent, beta 3 subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167535 CACNB3 9606 + 12:48813794-48828941 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301050 CACNB3-001 48818731-48828941 protein_coding
  ENST00000536187 CACNB3-004 48815587-48828219 protein_coding
  ENST00000540990 CACNB3-002 48814451-48828200 protein_coding
  ENST00000547230 CACNB3-018 48818909-48828941 protein_coding
  ENST00000547392 CACNB3-006 48818504-48828336 protein_coding
  ENST00000547693 CACNB3-020 48813794-48823984 retained_intron
  ENST00000547818 CACNB3-015 48818484-48826518 protein_coding
  ENST00000548279 CACNB3-017 48818787-48824697 protein_coding
  ENST00000548860 CACNB3-005 48814893-48828941 retained_intron
  ENST00000548874 CACNB3-009 48815591-48825484 nonsense_mediated_decay
  ENST00000549226 CACNB3-003 48814480-48825161 retained_intron
  ENST00000549971 CACNB3-014 48818406-48824312 processed_transcript
  ENST00000550064 CACNB3-024 48817866-48825720 protein_coding
  ENST00000550168 CACNB3-011 48815602-48824733 processed_transcript
  ENST00000550190 CACNB3-022 48823446-48828941 protein_coding
  ENST00000550391 CACNB3-008 48814432-48825724 nonsense_mediated_decay
  ENST00000550483 CACNB3-023 48823779-48826518 nonsense_mediated_decay
  ENST00000550771 CACNB3-016 48818793-48823961 retained_intron
  ENST00000551544 CACNB3-019 48818909-48828941 nonsense_mediated_decay
  ENST00000551716 CACNB3-010 48815600-48823972 retained_intron
  ENST00000552022 CACNB3-013 48818386-48824733 processed_transcript
  ENST00000552465 CACNB3-012 48815612-48817312 retained_intron
  ENST00000552480 CACNB3-021 48825115-48827868 retained_intron
  ENST00000552812 CACNB3-007 48819778-48821489 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301050ENST00000536187ENST00000540990ENST00000547230ENST00000547392ENST00000547818ENST00000548279ENST00000550190ENST00000552480ENST00000552812
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301050 1.779±0.00 0.914±0.00 N/A 5.198±1.14 1.123±0.00 1.948±1.39 0.526±0.00 1.776±0.00 0.196±0.00 2.859±0.00 N/A 19.752±17.44 2.835±0.22 3.379±0.00
ENST00000536187 N/A N/A 0.480±0.00 N/A N/A 2.051±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000540990 N/A N/A N/A N/A N/A N/A 0.022±0.00 N/A N/A N/A N/A 1.923±1.00 N/A 2.750±0.00
ENST00000547230 1.353±0.00 2.090±0.00 0.130±0.00 13.844±0.00 3.084±0.00 8.201±0.00 0.553±0.00 1.607±0.00 0.220±0.00 0.292±0.00 N/A 11.404±8.33 N/A 11.684±0.00
ENST00000547392 N/A N/A N/A N/A N/A N/A 0.253±0.00 N/A N/A N/A 0.707±0.00 N/A N/A N/A
ENST00000547818 N/A N/A N/A N/A 2.127±0.00 N/A 0.294±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000548279 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.846±0.00 N/A N/A N/A
ENST00000550190 3.629±0.00 N/A N/A 15.426±0.68 5.634±0.00 8.646±0.00 N/A N/A N/A N/A N/A N/A N/A 17.983±0.00
ENST00000552480 N/A N/A 0.570±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 6.012±0.00 4.084±0.00 N/A
ENST00000552812 N/A N/A N/A N/A N/A 1.051±0.00 N/A N/A N/A N/A N/A 0.602±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003DH CIL_0003DH_0002 CGP 12:48766194-48828941
CIL_0003DO CIL_0003DO_0002 CGP 12:48813794-48852842

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005245 IDA:IEA voltage-gated calcium channel activity
GO:0005515 IEA protein binding
GO:0005829 TAS cytosol
GO:0005891 IDA:IEA voltage-gated calcium channel complex
GO:0006810 TAS transport
GO:0006816 IDA calcium ion transport
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0016020 IDA membrane
GO:0016324 IEA apical plasma membrane
GO:0019901 IEA protein kinase binding
GO:0034765 IEA regulation of ion transmembrane transport
GO:0050852 IEA T cell receptor signaling pathway
GO:0051899 TAS membrane depolarization
GO:0070588 IEA calcium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001881 cacnb3a calcium channel, voltage-dependent, beta 3a protein_coding Danio_rerio
ENSDARG00000076030 cacnb3b calcium channel, voltage-dependent, beta 3b protein_coding Danio_rerio
ENSMUSG00000003352 Cacnb3 calcium channel, voltage-dependent, beta 3 subunit protein_coding Mus_musculus

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