C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: death-associated protein kinase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167657 DAPK3 9606 - 19:3958453-3971123 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301264 DAPK3-201 3958454-3969828 protein_coding
  ENST00000545797 DAPK3-001 3958453-3971070 protein_coding
  ENST00000593844 DAPK3-007 3964631-3969938 protein_coding
  ENST00000594894 DAPK3-008 3959639-3961159 protein_coding
  ENST00000595279 DAPK3-004 3958458-3961840 retained_intron
  ENST00000596311 DAPK3-005 3964322-3971123 protein_coding
  ENST00000601824 DAPK3-006 3964323-3970624 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301264ENST00000545797ENST00000595279ENST00000596311ENST00000601824
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301264 28.883±0.00 26.475±0.00 0.791±0.00 6.324±0.96 15.655±14.00 16.312±11.78 12.469±10.43 4.070±0.00 6.528±0.00 54.963±0.00 49.481±0.00 15.443±10.87 34.616±9.83 31.401±11.68
ENST00000545797 4.882±0.00 N/A N/A 6.256±0.00 N/A 7.428±0.00 N/A N/A N/A 11.889±0.00 N/A 6.768±6.24 N/A N/A
ENST00000595279 N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.665±0.00 N/A 3.432±2.39 N/A N/A
ENST00000596311 18.539±0.00 17.390±0.00 N/A 11.652±5.99 12.470±7.94 15.349±7.28 10.032±4.71 N/A 6.832±0.00 2.762±0.00 22.115±0.00 8.084±5.77 16.836±0.00 24.707±12.25
ENST00000601824 N/A N/A 0.874±0.00 N/A 3.702±0.00 N/A N/A N/A 3.180±0.00 1.210±0.00 N/A 2.608±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000775 IEA chromosome, centromeric region
GO:0000910 TAS cytokinesis
GO:0003824 IEA catalytic activity
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004683 IBA calmodulin-dependent protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006468 IDA:IEA protein phosphorylation
GO:0006915 IDA apoptotic process
GO:0006940 TAS regulation of smooth muscle contraction
GO:0007088 TAS regulation of mitosis
GO:0007346 IMP regulation of mitotic cell cycle
GO:0008360 IEA regulation of cell shape
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0010506 TAS regulation of autophagy
GO:0016020 IEA membrane
GO:0016568 IEA chromatin modification
GO:0016605 IEA PML body
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0017048 IDA Rho GTPase binding
GO:0017148 IDA negative regulation of translation
GO:0030182 IEA neuron differentiation
GO:0030335 IEA positive regulation of cell migration
GO:0035556 IDA intracellular signal transduction
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0042981 IBA regulation of apoptotic process
GO:0043065 IDA positive regulation of apoptotic process
GO:0043519 IEA regulation of myosin II filament organization
GO:0043522 IPI leucine zipper domain binding
GO:0045121 IEA membrane raft
GO:0046777 TAS protein autophosphorylation
GO:0051893 IDA regulation of focal adhesion assembly
GO:0071346 IDA cellular response to interferon-gamma
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway
GO:0097190 IEA apoptotic signaling pathway
GO:2000145 TAS regulation of cell motility
GO:2000249 TAS regulation of actin cytoskeleton reorganization
GO:2001241 IEA positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074447 dapk3 death-associated protein kinase 3 protein_coding Danio_rerio
ENSMUSG00000034974 Dapk3 death-associated protein kinase 3 protein_coding Mus_musculus

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