C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: keratin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167768 KRT1 9606 - 12:52674736-52680407 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000252244 KRT1-001 52674736-52680407 protein_coding
  ENST00000548765 KRT1-002 52675723-52677517 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastKidneyLiverOvaryPlacentaTestisENST00000252244ENST00000548765
Transcript ID Adipose Bladder Brain Breast Kidney Liver Ovary Placenta Testis
ENST00000252244 19.446±0.00 0.134±0.00 0.016±0.00 0.042±0.00 0.418±0.00 0.027±0.00 0.274±0.38 0.255±0.20 0.121±0.00
ENST00000548765 N/A N/A 0.059±0.00 0.765±0.00 N/A 0.165±0.00 N/A N/A 0.140±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00033Q CIL_00033Q_000G CGP 12:52644558-52680407
CIL_00033Q CIL_00033Q_0008 CGP 12:52674736-52703463

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001867 IPI complement activation, lectin pathway
GO:0001895 IEP retina homeostasis
GO:0004872 NAS receptor activity
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005856 TAS cytoskeleton
GO:0005882 IEA intermediate filament
GO:0005886 IEA plasma membrane
GO:0006979 NAS response to oxidative stress
GO:0016020 IDA membrane
GO:0030246 IPI carbohydrate binding
GO:0031012 IDA extracellular matrix
GO:0042730 NAS fibrinolysis
GO:0045095 IEA keratin filament
GO:0045765 NAS regulation of angiogenesis
GO:0050728 IEA negative regulation of inflammatory response
GO:0061436 IEA establishment of skin barrier
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017624 krt4 keratin 4 protein_coding Danio_rerio
ENSDARG00000043242 si:dkey-222f2.1 si:dkey-222f2.1 protein_coding Danio_rerio
ENSDARG00000058358 krt8 keratin 8 protein_coding Danio_rerio
ENSDARG00000058371 krt5 keratin 5 protein_coding Danio_rerio
ENSDARG00000058462 zgc:158846 zgc:158846 protein_coding Danio_rerio
ENSMUSG00000046834 Krt1 keratin 1 protein_coding Mus_musculus

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