C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: angiopoietin-like 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167772 ANGPTL4 9606 + 19:8363289-8374373 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301455 ANGPTL4-001 8364151-8374373 protein_coding
  ENST00000393962 ANGPTL4-002 8364169-8374331 protein_coding
  ENST00000593998 ANGPTL4-009 8364169-8374370 nonsense_mediated_decay
  ENST00000594348 ANGPTL4-011 8364169-8371262 retained_intron
  ENST00000594875 ANGPTL4-008 8364398-8374370 protein_coding
  ENST00000595079 ANGPTL4-003 8364156-8374288 nonsense_mediated_decay
  ENST00000597137 ANGPTL4-004 8363299-8371230 retained_intron
  ENST00000598255 ANGPTL4-010 8364166-8371261 retained_intron
  ENST00000599192 ANGPTL4-007 8363299-8364635 protein_coding
  ENST00000601770 ANGPTL4-005 8363411-8364578 protein_coding
  ENST00000601886 ANGPTL4-006 8363289-8364609 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301455ENST00000393962ENST00000593998ENST00000595079
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301455 82.567±0.00 37.647±0.00 33.611±0.00 23.832±21.70 47.512±0.00 18.564±9.45 12.311±10.96 37.023±0.00 N/A 7.907±7.05 61.197±39.88 16.280±0.00
ENST00000393962 N/A N/A N/A 2.000±0.00 N/A N/A N/A N/A N/A N/A 16.677±0.00 N/A
ENST00000593998 68.519±0.00 N/A N/A 36.194±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000595079 N/A N/A N/A N/A 1.198±0.00 N/A N/A N/A 2.099±0.00 N/A 21.259±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NQ CIL_0002NQ_0001 CGP 19:7926718-8445041
CIL_0000UT CIL_0000UT_0001 CGP 19:7958579-8445041

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001666 NAS response to hypoxia
GO:0004857 ISS enzyme inhibitor activity
GO:0005515 IPI protein binding
GO:0005576 IDA extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IEA:IDA extracellular space
GO:0030154 IEA cell differentiation
GO:0043066 IDA negative regulation of apoptotic process
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045766 TAS positive regulation of angiogenesis
GO:0051005 IDA negative regulation of lipoprotein lipase activity
GO:0051260 IEA protein homooligomerization
GO:0070328 ISS triglyceride homeostasis
GO:0072562 IDA blood microparticle
GO:2000352 IEA negative regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035859 angptl4 angiopoietin-like 4 protein_coding Danio_rerio
ENSMUSG00000002289 Angptl4 angiopoietin-like 4 protein_coding Mus_musculus

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