C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulin-like growth factor binding protein 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167779 IGFBP6 9606 + 12:53097436-53102345 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301464 IGFBP6-001 53097445-53102340 protein_coding
  ENST00000548176 IGFBP6-002 53097667-53101163 nonsense_mediated_decay
  ENST00000548547 IGFBP6-004 53097436-53102345 protein_coding
  ENST00000549628 IGFBP6-003 53098924-53102340 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301464ENST00000548176ENST00000548547ENST00000549628
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301464 59.876±0.00 25.199±0.00 1.395±0.00 5.734±1.64 37.032±29.32 100.975±96.28 9.311±5.75 14.097±13.49 22.774±17.81 37.093±29.08 8.095±1.15 53.036±68.88 13.413±6.13 61.213±45.40
ENST00000548176 64.755±0.00 28.007±0.00 N/A 5.328±0.00 90.824±0.00 142.774±0.00 8.444±0.00 10.302±0.00 2.707±0.00 38.197±0.00 5.029±0.00 2.994±0.00 8.176±0.00 47.602±34.45
ENST00000548547 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.160±0.00 N/A N/A N/A
ENST00000549628 N/A 10.012±0.00 N/A 3.194±0.00 36.955±0.00 94.118±0.00 8.600±0.00 8.304±7.10 2.507±0.00 59.181±0.00 6.612±0.00 29.703±27.67 14.921±8.62 52.938±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00033O CIL_00033O_0002 CGP 12:53064316-53102345
CIL_0006TD CIL_0006TD_0001 CGP 12:53097436-53124538

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0005520 IEA insulin-like growth factor binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0007165 NAS signal transduction
GO:0008285 TAS negative regulation of cell proliferation
GO:0031994 IEA insulin-like growth factor I binding
GO:0044267 TAS cellular protein metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070941 igfbp6a insulin-like growth factor binding protein 6a protein_coding Danio_rerio
ENSDARG00000090833 igfbp6b insulin-like growth factor binding protein 6b protein_coding Danio_rerio
ENSMUSG00000023046 Igfbp6 insulin-like growth factor binding protein 6 protein_coding Mus_musculus

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