C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sterol O-acyltransferase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167780 SOAT2 9606 + 12:53103518-53124538 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301466 SOAT2-001 53103518-53124538 protein_coding
  ENST00000542365 SOAT2-002 53103531-53124350 nonsense_mediated_decay
  ENST00000551896 SOAT2-003 53103518-53115516 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000301466ENST00000542365ENST00000551896
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000301466 N/A 0.064±0.00 N/A N/A N/A N/A N/A 0.040±0.00 N/A 0.118±0.00 N/A 0.080±0.02
ENST00000542365 0.099±0.00 0.043±0.00 0.134±0.00 0.016±0.00 0.118±0.00 0.039±0.00 0.099±0.00 N/A 0.013±0.00 0.781±0.00 0.094±0.04 0.144±0.00
ENST00000551896 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.071±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006TD CIL_0006TD_0001 CGP 12:53097436-53124538
CIL_0006TC CIL_0006TC_0001 CGP 12:53103518-53180909

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000062 IDA fatty-acyl-CoA binding
GO:0004772 IEA sterol O-acyltransferase activity
GO:0005783 IDA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005903 IDA brush border
GO:0008152 IEA metabolic process
GO:0008203 IDA cholesterol metabolic process
GO:0008374 IEA O-acyltransferase activity
GO:0010742 TAS macrophage derived foam cell differentiation
GO:0015485 IDA cholesterol binding
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016746 TAS transferase activity, transferring acyl groups
GO:0030299 IC intestinal cholesterol absorption
GO:0033344 IMP cholesterol efflux
GO:0034379 IMP very-low-density lipoprotein particle assembly
GO:0034435 IDA cholesterol esterification
GO:0034736 IDA cholesterol O-acyltransferase activity
GO:0042632 TAS cholesterol homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059824 soat2 sterol O-acyltransferase 2 protein_coding Danio_rerio
ENSMUSG00000023045 Soat2 sterol O-acyltransferase 2 protein_coding Mus_musculus

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