C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: latent transforming growth factor beta binding protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168056 LTBP3 9606 - 11:65538560-65558930 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301873 LTBP3-001 65538818-65558228 protein_coding
  ENST00000322147 LTBP3-002 65538805-65557959 protein_coding
  ENST00000524798 LTBP3-013 65552124-65554140 retained_intron
  ENST00000525443 LTBP3-008 65542407-65545770 retained_intron
  ENST00000526124 LTBP3-018 65540797-65541620 retained_intron
  ENST00000526825 LTBP3-005 65551972-65557765 nonsense_mediated_decay
  ENST00000526927 LTBP3-006 65539052-65557765 protein_coding
  ENST00000527339 LTBP3-019 65546196-65547565 protein_coding
  ENST00000527792 LTBP3-022 65551512-65552977 retained_intron
  ENST00000528516 LTBP3-003 65538991-65558038 nonsense_mediated_decay
  ENST00000528966 LTBP3-020 65547970-65551779 retained_intron
  ENST00000529189 LTBP3-009 65538819-65546759 protein_coding
  ENST00000529371 LTBP3-016 65539336-65540452 protein_coding
  ENST00000529582 LTBP3-011 65538817-65542038 retained_intron
  ENST00000529764 LTBP3-021 65548019-65551876 retained_intron
  ENST00000530426 LTBP3-014 65552112-65553727 protein_coding
  ENST00000530785 LTBP3-010 65538819-65544704 protein_coding
  ENST00000530866 LTBP3-004 65539411-65558930 protein_coding
  ENST00000530990 LTBP3-015 65540995-65541831 retained_intron
  ENST00000532661 LTBP3-017 65539195-65540683 protein_coding
  ENST00000532932 LTBP3-007 65538819-65548919 protein_coding
  ENST00000536982 LTBP3-201 65538560-65558228 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301873ENST00000322147ENST00000526927ENST00000528516ENST00000529189ENST00000530866ENST00000532932ENST00000536982
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301873 N/A N/A N/A N/A 25.679±0.00 19.281±0.00 9.065±0.00 23.331±0.00 N/A 19.509±16.33 N/A N/A N/A N/A
ENST00000322147 N/A N/A N/A N/A 1.412±0.00 N/A 11.911±0.00 N/A 3.557±0.00 20.333±0.00 N/A 138.980±105.60 15.030±0.00 N/A
ENST00000526927 14.258±0.00 20.892±0.00 N/A 26.076±0.00 32.539±0.00 17.328±16.07 N/A N/A N/A N/A N/A 45.440±0.00 19.255±0.00 26.598±0.00
ENST00000528516 N/A N/A 2.102±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 16.556±0.00
ENST00000529189 N/A N/A N/A N/A 3.514±0.00 N/A N/A 5.324±0.00 N/A N/A N/A N/A 29.274±0.00 N/A
ENST00000530866 N/A N/A N/A N/A N/A 1.045±0.00 N/A N/A 1.710±0.00 N/A N/A N/A N/A N/A
ENST00000532932 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.601±0.00 N/A N/A
ENST00000536982 12.997±0.00 15.618±0.00 N/A 9.472±6.13 1.409±0.00 17.232±0.00 4.609±3.73 8.857±6.92 7.597±0.00 20.288±0.00 8.789±5.92 19.123±17.46 25.001±7.79 17.422±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W1 CIL_0008W1_0001 VISTA 11:65187233-65790923

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IEA skeletal system development
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0030198 TAS extracellular matrix organization
GO:0030502 IEA negative regulation of bone mineralization
GO:0031012 IDA extracellular matrix
GO:0032331 IEA negative regulation of chondrocyte differentiation
GO:0036363 IMP transforming growth factor beta activation
GO:0045780 IEA positive regulation of bone resorption
GO:0046849 IEA bone remodeling
GO:0050431 IPI transforming growth factor beta binding
GO:0060349 IEA bone morphogenesis
GO:0060430 IEA lung saccule development
GO:0070062 IDA extracellular vesicular exosome
GO:1902462 IMP positive regulation of mesenchymal stem cell proliferation
GO:2000741 IMP positive regulation of mesenchymal stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035682 ltbp3 latent transforming growth factor beta binding protein 3 protein_coding Danio_rerio
ENSMUSG00000024940 Ltbp3 latent transforming growth factor beta binding protein 3 protein_coding Mus_musculus

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