C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cholinergic receptor, muscarinic 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168539 CHRM1 9606 - 11:62908679-62921807 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306960 CHRM1-001 62908679-62921681 protein_coding
  ENST00000536524 CHRM1-003 62910698-62916941 protein_coding
  ENST00000543973 CHRM1-002 62909738-62921807 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonKidneyLungOvaryPlacentaTestisENST00000306960ENST00000536524ENST00000543973
Transcript ID Brain Colon Kidney Lung Ovary Placenta Testis
ENST00000306960 2.874±0.00 N/A N/A 0.081±0.00 0.147±0.07 0.089±0.03 0.026±0.00
ENST00000536524 N/A N/A N/A N/A N/A N/A 0.358±0.00
ENST00000543973 N/A 0.054±0.00 0.069±0.00 0.156±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004435 TAS phosphatidylinositol phospholipase C activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006464 TAS cellular protein modification process
GO:0007165 TAS signal transduction
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007205 TAS protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007207 TAS phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
GO:0007213 TAS G-protein coupled acetylcholine receptor signaling pathway
GO:0007274 IEA neuromuscular synaptic transmission
GO:0007399 TAS nervous system development
GO:0008144 IEA drug binding
GO:0008283 TAS cell proliferation
GO:0008284 TAS positive regulation of cell proliferation
GO:0014069 IEA postsynaptic density
GO:0016020 TAS membrane
GO:0016021 IEA integral component of membrane
GO:0016907 IEA G-protein coupled acetylcholine receptor activity
GO:0030054 IEA cell junction
GO:0030425 IEA dendrite
GO:0032279 IEA asymmetric synapse
GO:0040012 IEA regulation of locomotion
GO:0043270 IGI positive regulation of ion transport
GO:0043679 IEA axon terminus
GO:0045211 IEA postsynaptic membrane
GO:0046541 IEA saliva secretion
GO:0050890 IEA cognition
GO:0090316 IEA positive regulation of intracellular protein transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009121 CHRM1 (1 of 2) cholinergic receptor, muscarinic 1 protein_coding Danio_rerio
ENSDARG00000037292 CU019640.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000032773 Chrm1 cholinergic receptor, muscarinic 1, CNS protein_coding Mus_musculus

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