C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inhibitor of growth family, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168556 ING2 9606 + 4:183504994-183511096 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302327 ING2-001 183504994-183511096 protein_coding
  ENST00000412117 ING2-002 183506082-183510643 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302327ENST00000412117
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302327 2.462±0.00 3.129±0.00 0.849±0.00 3.211±0.86 2.009±1.74 2.370±0.78 1.305±1.10 3.389±2.00 1.409±0.11 2.016±1.26 3.509±3.06 10.186±6.28 7.556±3.67 14.810±3.58
ENST00000412117 1.534±0.00 1.250±0.00 N/A N/A 1.303±0.98 N/A N/A 2.144±0.00 1.253±0.00 1.774±0.00 3.467±0.00 N/A 1.731±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0003682 IEA chromatin binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007141 ISS male meiosis I
GO:0007165 TAS signal transduction
GO:0007283 ISS spermatogenesis
GO:0007286 ISS spermatid development
GO:0008270 IEA zinc ion binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0016568 ISS chromatin modification
GO:0016580 IDA Sin3 complex
GO:0016602 IDA CCAAT-binding factor complex
GO:0030317 ISS sperm motility
GO:0030511 IDA positive regulation of transforming growth factor beta receptor signaling pathway
GO:0032403 IDA protein complex binding
GO:0035064 IDA methylated histone binding
GO:0035091 IDA phosphatidylinositol binding
GO:0040008 IEA regulation of growth
GO:0043065 IEA positive regulation of apoptotic process
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048133 ISS male germ-line stem cell asymmetric division
GO:0072520 ISS seminiferous tubule development
GO:1902166 TAS negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2000772 NAS regulation of cellular senescence
GO:2001020 NAS regulation of response to DNA damage stimulus
GO:2001234 IEA negative regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013042 ing2 inhibitor of growth family, member 2 protein_coding Danio_rerio
ENSMUSG00000063049 Ing2 inhibitor of growth family, member 2 protein_coding Mus_musculus

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