C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: methionine adenosyltransferase II, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168906 MAT2A 9606 + 2:85539165-85545280 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306434 MAT2A-001 85539165-85545280 protein_coding
  ENST00000409017 MAT2A-007 85539642-85543608 protein_coding
  ENST00000465151 MAT2A-010 85539168-85541454 retained_intron
  ENST00000469221 MAT2A-011 85539168-85541656 retained_intron
  ENST00000481412 MAT2A-006 85539604-85543218 retained_intron
  ENST00000490878 MAT2A-012 85541482-85542129 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306434ENST00000409017
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306434 12.763±0.00 11.354±2.19 9.887±0.00 16.249±2.42 3.320±0.00 12.419±0.00 17.850±2.04 10.340±0.00 13.854±1.17 38.579±27.57 13.517±4.57 24.269±0.00
ENST00000409017 N/A N/A 14.957±0.00 N/A 2.602±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AX CIL_0009AX_0001 VISTA 2:84977509-85579132
CIL_0007WR CIL_0007WR_0001 VISTA 2:85469895-86073896
CIL_00084P CIL_00084P_0001 VISTA 2:85470344-86073882

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000096 TAS sulfur amino acid metabolic process
GO:0004478 IDA:IEA methionine adenosyltransferase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006556 IEA S-adenosylmethionine biosynthetic process
GO:0006730 IEA one-carbon metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0032259 TAS methylation
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0048269 IDA methionine adenosyltransferase complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037121 mat2ab methionine adenosyltransferase II, alpha b protein_coding Danio_rerio
ENSDARG00000040334 mat2aa methionine adenosyltransferase II, alpha a protein_coding Danio_rerio
ENSMUSG00000053907 Mat2a methionine adenosyltransferase II, alpha protein_coding Mus_musculus

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