C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: R-spondin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169218 RSPO1 9606 - 1:37611350-37634923 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356545 RSPO1-003 37611639-37634923 protein_coding
  ENST00000401068 RSPO1-002 37611812-37634616 protein_coding
  ENST00000612451 RSPO1-004 37611350-37634665 protein_coding
  ENST00000615459 RSPO1-001 37611350-37634665 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000356545ENST00000401068ENST00000612451ENST00000615459
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000356545 N/A 0.108±0.00 N/A N/A 0.593±0.00 0.023±0.00 0.229±0.00 N/A 0.435±0.34 1.816±1.11 0.247±0.00 0.187±0.09
ENST00000401068 N/A N/A N/A N/A N/A N/A N/A 0.040±0.00 0.210±0.00 0.070±0.00 N/A N/A
ENST00000612451 N/A 0.103±0.00 N/A 0.718±0.00 N/A 0.057±0.00 0.086±0.00 N/A N/A 0.814±0.75 0.093±0.00 0.463±0.00
ENST00000615459 0.044±0.00 0.145±0.00 0.026±0.00 0.294±0.16 0.296±0.14 N/A 0.152±0.00 N/A 1.109±0.00 0.350±0.00 0.126±0.04 0.659±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001664 IPI G-protein coupled receptor binding
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0002090 IDA regulation of receptor internalization
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0007140 IEA male meiosis
GO:0008201 IEA heparin binding
GO:0010468 IEA regulation of gene expression
GO:0030177 IDA positive regulation of Wnt signaling pathway
GO:0060070 IEA canonical Wnt signaling pathway
GO:0090263 IDA positive regulation of canonical Wnt signaling pathway
GO:2000052 IEA positive regulation of non-canonical Wnt signaling pathway
GO:2000254 IEA regulation of male germ cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039957 rspo1 R-spondin homolog (Xenopus laevis) protein_coding Danio_rerio
ENSMUSG00000028871 Rspo1 R-spondin homolog (Xenopus laevis) protein_coding Mus_musculus

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