C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X-C motif) ligand 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169248 CXCL11 9606 - 4:76033682-76041415 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306621 CXCL11-001 76033682-76036197 protein_coding
  ENST00000503860 CXCL11-003 76034690-76041415 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306621ENST00000503860
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306621 0.068±0.00 0.115±0.00 0.131±0.01 0.709±0.00 0.010±0.00 0.597±0.57 N/A 0.039±0.01 3.442±2.87 N/A 0.390±0.16 0.413±0.36 0.202±0.17
ENST00000503860 N/A N/A 0.132±0.00 N/A N/A N/A 0.267±0.24 N/A N/A 0.027±0.00 0.137±0.00 0.176±0.00 0.054±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00071M CIL_00071M_0001 CGP 4:76001275-76112802
CIL_00071H CIL_00071H_0001 CGP 4:76011184-76112802
CIL_0008VL CIL_0008VL_0001 VISTA 4:76031495-76631676

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006935 IDA chemotaxis
GO:0006954 IEA inflammatory response
GO:0006955 IEA immune response
GO:0007165 TAS signal transduction
GO:0007267 TAS cell-cell signaling
GO:0008009 IDA:IEA chemokine activity
GO:0008201 IMP heparin binding
GO:0010818 IMP T cell chemotaxis
GO:0030816 IDA positive regulation of cAMP metabolic process
GO:0042127 IMP regulation of cell proliferation
GO:0043950 IDA positive regulation of cAMP-mediated signaling
GO:0048248 IDA CXCR3 chemokine receptor binding
GO:0051281 IDA positive regulation of release of sequestered calcium ion into cytosol
GO:0070098 IMP chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000060183 Cxcl11 chemokine (C-X-C motif) ligand 11 polymorphic_pseudogene Mus_musculus

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