C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adrenoceptor beta 2, surface
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169252 ADRB2 9606 + 5:148825245-148828687 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305988 ADRB2-001 148825245-148828687 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000305988
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000305988 10.656±0.00 1.543±0.00 0.163±0.00 0.466±0.06 3.297±1.60 0.956±0.39 0.910±0.33 0.383±0.00 1.000±0.21 2.692±0.00 1.302±0.00 0.284±0.05 2.991±1.84 0.285±0.15

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001993 IEA regulation of systemic arterial blood pressure by norepinephrine-epinephrine
GO:0002024 IEA diet induced thermogenesis
GO:0002025 IEA vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0002028 IEA regulation of sodium ion transport
GO:0002032 IDA desensitization of G-protein coupled receptor protein signaling pathway by arrestin
GO:0004930 IEA G-protein coupled receptor activity
GO:0004941 IDA beta2-adrenergic receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005764 TAS lysosome
GO:0005768 TAS endosome
GO:0005886 IDA plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006898 IDA receptor-mediated endocytosis
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007171 TAS activation of transmembrane receptor protein tyrosine kinase activity
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007188 TAS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007189 IEA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 IDA activation of adenylate cyclase activity
GO:0008179 IEA adenylate cyclase binding
GO:0008333 TAS endosome to lysosome transport
GO:0009409 IEA response to cold
GO:0015459 IDA potassium channel regulator activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0019899 IEA enzyme binding
GO:0030501 IEA positive regulation of bone mineralization
GO:0031398 IMP positive regulation of protein ubiquitination
GO:0031649 IEA heat generation
GO:0040015 IEA negative regulation of multicellular organism growth
GO:0042312 IEA regulation of vasodilation
GO:0042803 IDA protein homodimerization activity
GO:0043235 IDA receptor complex
GO:0043410 IDA positive regulation of MAPK cascade
GO:0045453 IEA bone resorption
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0045986 IEA negative regulation of smooth muscle contraction
GO:0050873 IEA brown fat cell differentiation
GO:0051380 IDA norepinephrine binding
GO:0071875 IEA adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054510 adrb2b adrenergic receptor, beta 2b protein_coding Danio_rerio
ENSDARG00000088124 adrb2a adrenergic receptor, beta 2a protein_coding Danio_rerio
ENSMUSG00000045730 Adrb2 adrenergic receptor, beta 2 protein_coding Mus_musculus

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