C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuregulin 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169752 NRG4 9606 - 15:75935969-76059795 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000394907 NRG4-001 75943009-76012444 protein_coding
  ENST00000461391 NRG4-002 75940936-76012422 nonsense_mediated_decay
  ENST00000472094 NRG4-003 75941973-76012221 nonsense_mediated_decay
  ENST00000498750 NRG4-004 75959074-76012077 nonsense_mediated_decay
  ENST00000562114 NRG4-005 75943234-76012433 nonsense_mediated_decay
  ENST00000563204 NRG4-012 75955932-76012422 nonsense_mediated_decay
  ENST00000563582 NRG4-010 76052098-76057254 processed_transcript
  ENST00000563910 NRG4-008 75955932-76059795 protein_coding
  ENST00000565661 NRG4-006 75943166-76059728 nonsense_mediated_decay
  ENST00000566417 NRG4-011 75936264-76057017 nonsense_mediated_decay
  ENST00000567126 NRG4-009 75961930-76059733 nonsense_mediated_decay
  ENST00000567467 NRG4-015 75935969-75942772 processed_transcript
  ENST00000567936 NRG4-013 75955932-76012394 nonsense_mediated_decay
  ENST00000568073 NRG4-007 75943044-76011287 nonsense_mediated_decay
  ENST00000568203 NRG4-016 76005740-76009295 processed_transcript
  ENST00000569343 NRG4-014 75935969-75945845 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainKidneyLungMuscleOvaryPlacentaTestisENST00000461391ENST00000472094
Transcript ID Brain Kidney Lung Muscle Ovary Placenta Testis
ENST00000461391 0.975±0.00 1.010±0.00 0.501±0.00 N/A 0.803±0.00 0.751±0.00 2.091±1.12
ENST00000472094 N/A N/A N/A 1.276±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00024C CIL_00024C_0001 CGP 15:75843285-75942510
CIL_000249 CIL_000249_0001 CGP 15:75903859-76059795
CIL_00024A CIL_00024A_0001 CGP 15:75935969-76229121

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005886 IEA plasma membrane
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008083 IEA growth factor activity
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0016021 IEA integral component of membrane
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000032311 Nrg4 neuregulin 4 protein_coding Mus_musculus

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