C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: wingless-type MMTV integration site family, member 10B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169884 WNT10B 9606 - 12:48965340-48971763 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301061 WNT10B-001 48965340-48971763 protein_coding
  ENST00000403957 WNT10B-002 48965556-48971718 protein_coding
  ENST00000407467 WNT10B-003 48965405-48971498 protein_coding
  ENST00000413630 WNT10B-006 48968296-48970756 protein_coding
  ENST00000420388 WNT10B-004 48970120-48970889 protein_coding
  ENST00000475740 WNT10B-005 48970120-48970652 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301061ENST00000403957ENST00000407467
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301061 N/A 0.332±0.00 0.838±0.00 0.500±0.00 0.022±0.00 0.073±0.00 N/A 0.192±0.00 N/A N/A 0.195±0.14 0.932±0.76 0.520±0.07
ENST00000403957 0.041±0.00 0.354±0.00 0.555±0.00 N/A 0.035±0.00 N/A N/A 0.222±0.21 0.245±0.00 0.038±0.00 0.188±0.06 0.653±0.00 N/A
ENST00000407467 N/A N/A 0.533±0.00 N/A 0.100±0.00 N/A 0.098±0.00 N/A 0.517±0.00 N/A N/A 0.240±0.00 2.107±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00000G CIL_00000G_0001 CGP 12:48935723-48971763
CIL_00033L CIL_00033L_0002 CGP 12:48965340-48981676

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 IEA G2/M transition of mitotic cell cycle
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0002062 IEP chondrocyte differentiation
GO:0005102 IEA receptor binding
GO:0005109 IBA frizzled binding
GO:0005576 TAS:IEA extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 NAS extracellular space
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006629 IEA lipid metabolic process
GO:0007050 IEA cell cycle arrest
GO:0007224 IEA smoothened signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0008284 IEA positive regulation of cell proliferation
GO:0010971 IEA positive regulation of G2/M transition of mitotic cell cycle
GO:0014835 IEA myoblast differentiation involved in skeletal muscle regeneration
GO:0016055 IMP:IEA Wnt signaling pathway
GO:0030182 ISS neuron differentiation
GO:0030501 IEA positive regulation of bone mineralization
GO:0030858 IEA positive regulation of epithelial cell differentiation
GO:0032434 IEA regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043065 IMP positive regulation of apoptotic process
GO:0043403 IEA skeletal muscle tissue regeneration
GO:0045165 IBA cell fate commitment
GO:0045598 IEA regulation of fat cell differentiation
GO:0045599 IDA negative regulation of fat cell differentiation
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045778 IEA positive regulation of ossification
GO:0045899 IEA positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048018 IC receptor agonist activity
GO:0048641 IEA regulation of skeletal muscle tissue development
GO:0048741 IEA skeletal muscle fiber development
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0050821 IDA protein stabilization
GO:0050909 IEA sensory perception of taste
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051246 IEA regulation of protein metabolic process
GO:0051885 IEA positive regulation of anagen
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060346 IEA bone trabecula formation
GO:0061196 IEA fungiform papilla development
GO:0071300 ISS cellular response to retinoic acid
GO:0071310 IEA cellular response to organic substance
GO:0071320 IEA cellular response to cAMP
GO:0071374 IEA cellular response to parathyroid hormone stimulus
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071425 IDA hematopoietic stem cell proliferation
GO:0071464 IEA cellular response to hydrostatic pressure
GO:0090263 IEA positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040925 wnt10b wingless-type MMTV integration site family, member 10b protein_coding Danio_rerio
ENSMUSG00000022996 Wnt10b wingless-type MMTV integration site family, member 10B protein_coding Mus_musculus

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