C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glucuronidase, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169919 GUSB 9606 - 7:65960684-65982314 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000304895 GUSB-001 65960684-65982314 protein_coding
  ENST00000421103 GUSB-002 65960701-65982211 protein_coding
  ENST00000430730 GUSB-008 65960698-65982215 nonsense_mediated_decay
  ENST00000446111 GUSB-004 65975852-65982213 nonsense_mediated_decay
  ENST00000447929 GUSB-007 65960698-65982196 nonsense_mediated_decay
  ENST00000461622 GUSB-016 65964146-65967908 retained_intron
  ENST00000462371 GUSB-015 65964330-65974847 retained_intron
  ENST00000465785 GUSB-013 65974294-65979508 processed_transcript
  ENST00000466883 GUSB-005 65960688-65976160 retained_intron
  ENST00000475316 GUSB-009 65974503-65982088 processed_transcript
  ENST00000476486 GUSB-010 65975012-65981971 processed_transcript
  ENST00000478118 GUSB-011 65979478-65980829 processed_transcript
  ENST00000479038 GUSB-012 65974357-65980411 processed_transcript
  ENST00000489482 GUSB-014 65974404-65975006 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000304895ENST00000421103ENST00000430730ENST00000446111ENST00000447929ENST00000465785ENST00000466883ENST00000478118
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000304895 22.685±0.00 7.417±0.00 1.658±0.00 N/A 6.054±1.94 N/A N/A 9.452±2.31 21.776±0.00 9.090±7.58 5.956±0.00 24.278±4.96 32.906±10.55 10.303±0.00
ENST00000421103 18.505±0.00 8.988±0.00 N/A 4.828±0.00 9.723±0.00 9.894±0.00 1.402±0.00 N/A 18.376±0.00 14.507±0.00 N/A 10.876±0.98 N/A 9.699±0.00
ENST00000430730 N/A 5.446±0.00 0.860±0.00 2.160±1.41 4.119±0.00 6.275±0.00 N/A 7.829±0.00 N/A 1.338±0.00 N/A 21.030±0.00 8.561±0.00 7.600±0.80
ENST00000446111 N/A N/A 1.127±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000447929 N/A N/A N/A N/A N/A N/A 0.965±0.88 N/A N/A N/A N/A N/A 4.975±0.00 9.666±0.00
ENST00000465785 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.184±0.00 N/A N/A
ENST00000466883 N/A 3.543±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.454±0.00 N/A N/A N/A
ENST00000478118 N/A N/A N/A N/A N/A N/A 0.960±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004553 IEA hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004566 TAS beta-glucuronidase activity
GO:0005764 IEA lysosome
GO:0005975 TAS:IEA carbohydrate metabolic process
GO:0006027 TAS glycosaminoglycan catabolic process
GO:0016020 IDA membrane
GO:0030203 TAS glycosaminoglycan metabolic process
GO:0030212 TAS hyaluronan metabolic process
GO:0030214 TAS hyaluronan catabolic process
GO:0043202 TAS lysosomal lumen
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063126 GUSB (1 of 2) glucuronidase, beta protein_coding Danio_rerio
ENSDARG00000095529 gusb glucuronidase, beta protein_coding Danio_rerio
ENSMUSG00000025534 Gusb glucuronidase, beta protein_coding Mus_musculus

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