C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169967 MAP3K2 9606 - 2:127298730-127388465 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344908 MAP3K2-002 127307404-127343229 protein_coding
  ENST00000409179 MAP3K2-003 127337759-127387932 protein_coding
  ENST00000409947 MAP3K2-001 127298730-127388465 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonLiverLungMuscleOvaryPlacentaTestisENST00000344908ENST00000409947
Transcript ID Adrenal Bladder Brain Breast Colon Liver Lung Muscle Ovary Placenta Testis
ENST00000344908 N/A 1.825±0.00 2.004±0.00 3.878±0.00 N/A 2.964±0.00 3.695±0.00 1.653±0.00 7.583±0.00 N/A N/A
ENST00000409947 3.233±0.00 N/A 1.354±0.00 N/A 0.744±0.25 0.805±0.00 N/A N/A 1.803±0.00 0.169±0.00 2.556±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000186 IEA activation of MAPKK activity
GO:0000187 TAS activation of MAPK activity
GO:0004672 IDA:IEA protein kinase activity
GO:0004674 TAS protein serine/threonine kinase activity
GO:0004709 IEA MAP kinase kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IEA cytosol
GO:0006468 IEA protein phosphorylation
GO:0007257 TAS activation of JUN kinase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019901 IPI protein kinase binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0071260 IEP cellular response to mechanical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062884 MAP3K2 mitogen-activated protein kinase kinase kinase 2 protein_coding Danio_rerio
ENSMUSG00000024383 Map3k2 mitogen-activated protein kinase kinase kinase 2 protein_coding Mus_musculus

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