C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170099 SERPINA6 9606 - 14:94304248-94323394 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341584 SERPINA6-001 94304249-94323394 protein_coding
  ENST00000555056 SERPINA6-003 94304248-94323319 nonsense_mediated_decay
  ENST00000557225 SERPINA6-004 94314240-94323389 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000341584ENST00000555056ENST00000557225
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000341584 4.216±0.00 N/A 0.460±0.16 0.341±0.14 0.011±0.00 38.318±33.29 206.823±0.00 N/A 0.987±0.88 0.068±0.07 0.189±0.00
ENST00000555056 N/A N/A 0.373±0.00 N/A N/A N/A N/A N/A N/A 0.026±0.00 N/A
ENST00000557225 N/A 0.033±0.00 N/A N/A N/A N/A N/A 0.470±0.00 N/A N/A 0.082±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003QR CIL_0003QR_0001 CGP 14:94280455-94323394
CIL_000598 CIL_000598_000A CGP 14:94304248-94390693

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005496 IDA steroid binding
GO:0005615 IBA extracellular space
GO:0006810 IEA transport
GO:0008211 IEA glucocorticoid metabolic process
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074712 si:ch211-186e20.2 si:ch211-186e20.2 protein_coding Danio_rerio
ENSDARG00000077960 si:ch211-186e20.7 si:ch211-186e20.7 protein_coding Danio_rerio
ENSDARG00000087143 serpina7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 protein_coding Danio_rerio
ENSDARG00000090286 serpina1 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 protein_coding Danio_rerio
ENSDARG00000090850 serpina1l serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like protein_coding Danio_rerio
ENSDARG00000090916 CR559930.2 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000091136 zgc:174259 zgc:174259 protein_coding Danio_rerio
ENSDARG00000091800 zgc:174260 zgc:174260 protein_coding Danio_rerio
ENSMUSG00000060807 Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 protein_coding Mus_musculus

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