C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: keratin 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170421 KRT8 9606 - 12:52897187-52949954 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000293308 KRT8-002 52897194-52905072 protein_coding
  ENST00000546542 KRT8-015 52904676-52907060 protein_coding
  ENST00000546583 KRT8-005 52897208-52905052 retained_intron
  ENST00000546826 KRT8-013 52899935-52949882 protein_coding
  ENST00000546897 KRT8-003 52897281-52949824 protein_coding
  ENST00000546900 KRT8-017 52900588-52903648 protein_coding
  ENST00000546921 KRT8-009 52949216-52949954 retained_intron
  ENST00000547031 KRT8-020 52898469-52901867 retained_intron
  ENST00000547176 KRT8-019 52899996-52901947 nonsense_mediated_decay
  ENST00000547413 KRT8-016 52901864-52906618 protein_coding
  ENST00000548998 KRT8-014 52900008-52949776 protein_coding
  ENST00000549176 KRT8-018 52899794-52902204 retained_intron
  ENST00000549198 KRT8-012 52948484-52949831 processed_transcript
  ENST00000550170 KRT8-008 52897216-52905044 retained_intron
  ENST00000551318 KRT8-010 52948651-52949920 processed_transcript
  ENST00000552150 KRT8-004 52897297-52926469 protein_coding
  ENST00000552551 KRT8-001 52897187-52949842 protein_coding
  ENST00000552877 KRT8-011 52948650-52949874 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000293308ENST00000546826ENST00000546900ENST00000548998ENST00000549176ENST00000549198ENST00000552150
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000293308 3.558±0.00 3.499±0.00 4.980±0.00 0.718±0.00 30.611±4.78 101.049±3.01 14.389±12.28 91.705±60.36 68.175±52.79 71.890±64.23 0.344±0.00 164.761±137.34 1056.576±517.25 13.333±7.04
ENST00000546826 N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.969±0.00 N/A N/A N/A N/A
ENST00000546900 N/A N/A N/A 0.117±0.00 N/A N/A N/A N/A N/A N/A 0.651±0.00 N/A N/A N/A
ENST00000548998 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.038±0.00 N/A N/A N/A
ENST00000549176 N/A N/A 6.787±0.00 N/A 56.232±0.00 91.758±0.00 3.350±0.00 N/A 19.272±0.00 N/A N/A 82.508±0.00 443.267±0.00 N/A
ENST00000549198 N/A N/A N/A 1.122±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000552150 N/A N/A N/A N/A 31.354±0.00 56.305±0.00 N/A N/A N/A N/A N/A 384.602±347.16 923.425±0.00 3.695±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00038V CIL_00038V_0001 CGP 12:52837804-52949954
CIL_0006T8 CIL_0006T8_0001 CGP 12:52897187-52952901

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005882 IDA:IEA intermediate filament
GO:0005911 IEA cell-cell junction
GO:0016010 IEA dystrophin-associated glycoprotein complex
GO:0016032 IEA viral process
GO:0030018 IEA Z disc
GO:0032403 IEA protein complex binding
GO:0033209 IEA tumor necrosis factor-mediated signaling pathway
GO:0042383 IEA sarcolemma
GO:0043034 IEA costamere
GO:0045095 IEA keratin filament
GO:0045214 IEA sarcomere organization
GO:0051599 IEA response to hydrostatic pressure
GO:0051707 IEA response to other organism
GO:0060706 IEA cell differentiation involved in embryonic placenta development
GO:0070062 IDA extracellular vesicular exosome
GO:0071944 IEA cell periphery
GO:0097110 IPI scaffold protein binding
GO:0097191 IEA extrinsic apoptotic signaling pathway
GO:0097284 IEA hepatocyte apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017624 krt4 keratin 4 protein_coding Danio_rerio
ENSDARG00000043242 si:dkey-222f2.1 si:dkey-222f2.1 protein_coding Danio_rerio
ENSDARG00000058358 krt8 keratin 8 protein_coding Danio_rerio
ENSDARG00000058371 krt5 keratin 5 protein_coding Danio_rerio
ENSDARG00000058462 zgc:158846 zgc:158846 protein_coding Danio_rerio
ENSMUSG00000049382 Krt8 keratin 8 protein_coding Mus_musculus

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