C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: marginal zone B and B1 cell-specific protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170476 MZB1 9606 - 5:139387480-139390081 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302125 MZB1-002 139387568-139389914 protein_coding
  ENST00000417694 MZB1-003 139387486-139389913 nonsense_mediated_decay
  ENST00000503120 MZB1-005 139387569-139389883 retained_intron
  ENST00000503351 MZB1-007 139387785-139389848 nonsense_mediated_decay
  ENST00000503481 MZB1-001 139387480-139390081 nonsense_mediated_decay
  ENST00000509591 MZB1-008 139388596-139389914 retained_intron
  ENST00000511979 MZB1-006 139387595-139388762 retained_intron
  ENST00000513389 MZB1-004 139387568-139389895 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000302125ENST00000503120ENST00000503351ENST00000509591ENST00000511979ENST00000513389
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000302125 0.968±0.00 71.351±0.00 N/A 7.946±0.74 3.296±0.66 N/A 1.250±0.00 1.010±0.14 13.309±11.14 6.557±2.88 0.434±0.00 0.355±0.00
ENST00000503120 N/A 4.904±0.00 N/A 0.823±0.00 0.635±0.45 N/A N/A 0.061±0.00 N/A 0.750±0.00 N/A N/A
ENST00000503351 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.180±0.48 0.363±0.02 0.085±0.00
ENST00000509591 0.096±0.00 N/A 0.228±0.00 N/A N/A 0.202±0.05 0.147±0.00 0.228±0.00 N/A N/A 0.158±0.00 0.362±0.00
ENST00000511979 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.346±0.00
ENST00000513389 N/A 30.650±0.00 0.152±0.09 N/A 0.680±0.00 0.407±0.00 1.107±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000543 CIL_000543_0001 CGP 5:139367196-139390081
CIL_000544 CIL_000544_0001 CGP 5:139387480-139395713

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002642 ISS positive regulation of immunoglobulin biosynthetic process
GO:0005515 IPI protein binding
GO:0005576 IDA extracellular region
GO:0005737 IDA cytoplasm
GO:0005788 ISS endoplasmic reticulum lumen
GO:0006915 IEA apoptotic process
GO:0008284 IDA positive regulation of cell proliferation
GO:0030888 ISS regulation of B cell proliferation
GO:0033622 ISS integrin activation
GO:0034663 ISS endoplasmic reticulum chaperone complex
GO:0042127 ISS regulation of cell proliferation
GO:2001274 ISS negative regulation of glucose import in response to insulin stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000024353 Mzb1 marginal zone B and B1 cell-specific protein 1 protein_coding Mus_musculus

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