C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tripartite motif containing 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171206 TRIM8 9606 + 10:102644496-102658407 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302424 TRIM8-001 102644496-102658407 protein_coding
  ENST00000462202 TRIM8-003 102644887-102656954 protein_coding
  ENST00000479004 TRIM8-004 102655281-102657087 processed_transcript
  ENST00000487927 TRIM8-002 102649219-102656969 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302424ENST00000462202ENST00000487927
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302424 48.720±0.00 18.703±0.00 7.042±0.00 16.235±8.27 38.791±30.80 14.057±10.32 11.228±9.60 16.160±10.73 7.642±2.89 30.962±28.17 13.471±7.52 26.374±17.05 26.626±9.80 18.420±0.83
ENST00000462202 N/A 25.058±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000487927 42.611±0.00 N/A N/A N/A 81.467±0.00 24.962±0.00 N/A N/A N/A N/A N/A N/A 12.953±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MQ CIL_0008MQ_0001 VISTA 10:102469546-103070739
CIL_00065X CIL_00065X_0001 CGP 10:102503987-102658407
CIL_0001HP CIL_0001HP_0002 CGP 10:102644496-102714407

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0008270 IEA:NAS zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016605 IDA PML body
GO:0016874 IEA ligase activity
GO:0032897 IEA negative regulation of viral transcription
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0045087 IDA innate immune response
GO:0046597 IEA negative regulation of viral entry into host cell
GO:0046872 IEA metal ion binding
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:1902187 IDA negative regulation of viral release from host cell

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060729 trim8b tripartite motif-containing 8b protein_coding Danio_rerio
ENSDARG00000090512 trim8a tripartite motif containing 8a protein_coding Danio_rerio
ENSMUSG00000025034 Trim8 tripartite motif-containing 8 protein_coding Mus_musculus

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