C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: secretogranin II
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171951 SCG2 9606 - 2:223596940-223602503 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305409 SCG2-001 223596940-223602503 protein_coding
  ENST00000421386 SCG2-003 223598851-223602284 protein_coding
  ENST00000433889 SCG2-002 223598906-223602361 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000305409ENST00000421386ENST00000433889
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000305409 0.996±0.00 0.032±0.00 0.056±0.00 24.735±14.07 0.736±0.69 3.869±3.08 0.048±0.02 0.117±0.09 0.077±0.00 0.198±0.17 0.021±0.01 1.024±0.60 0.271±0.14 0.192±0.06
ENST00000421386 N/A N/A N/A N/A N/A 0.801±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000433889 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.542±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004AL CIL_0004AL_0002 CGP 2:223051814-223602503
CIL_0004AM CIL_0004AM_0003 CGP 2:223596940-223838027

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IDA MAPK cascade
GO:0001525 IDA angiogenesis
GO:0001937 TAS negative regulation of endothelial cell proliferation
GO:0001938 IDA positive regulation of endothelial cell proliferation
GO:0005125 IDA cytokine activity
GO:0005615 IDA extracellular space
GO:0006928 IDA cellular component movement
GO:0006954 TAS inflammatory response
GO:0009306 TAS protein secretion
GO:0030141 IEA secretory granule
GO:0035556 IDA intracellular signal transduction
GO:0042056 IDA chemoattractant activity
GO:0043542 TAS endothelial cell migration
GO:0048245 IDA eosinophil chemotaxis
GO:0050918 IDA positive chemotaxis
GO:0050930 IDA induction of positive chemotaxis
GO:2000352 IDA negative regulation of endothelial cell apoptotic process
GO:2001237 IDA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017470 scg2a secretogranin II (chromogranin C) a protein_coding Danio_rerio
ENSDARG00000038574 scg2b secretogranin II (chromogranin C), b protein_coding Danio_rerio
ENSMUSG00000050711 Scg2 secretogranin II protein_coding Mus_musculus

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