C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mal, T-cell differentiation protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172005 MAL 9606 + 2:95025677-95053996 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309988 MAL-001 95025684-95053996 protein_coding
  ENST00000349807 MAL-004 95025793-95053992 protein_coding
  ENST00000353004 MAL-002 95025793-95053992 protein_coding
  ENST00000354078 MAL-003 95025793-95053992 protein_coding
  ENST00000489399 MAL-005 95025677-95044633 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000309988ENST00000349807ENST00000353004ENST00000354078
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000309988 2.974±0.00 9.233±0.00 12.173±0.00 62.910±52.21 0.377±0.00 22.851±0.00 1.926±0.00 286.032±0.00 0.294±0.09 12.540±11.54 N/A 10.837±10.95 4.458±1.34 0.668±0.17
ENST00000349807 N/A N/A 4.961±0.00 10.846±0.00 0.309±0.00 N/A 0.077±0.00 0.349±0.00 N/A N/A N/A 1.935±0.00 N/A N/A
ENST00000353004 N/A N/A 4.383±0.00 N/A N/A N/A N/A N/A N/A N/A 0.394±0.00 N/A N/A N/A
ENST00000354078 0.614±0.00 N/A N/A N/A 0.574±0.00 0.307±0.00 0.276±0.00 N/A N/A 4.152±0.00 N/A 4.073±0.00 N/A 0.673±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004I3 CIL_0004I3_0002 CGP 2:95025677-95149434

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001766 TAS membrane raft polarization
GO:0005515 IPI protein binding
GO:0005768 TAS endosome
GO:0005783 IDA endoplasmic reticulum
GO:0005887 TAS integral component of plasma membrane
GO:0006915 NAS apoptotic process
GO:0007417 TAS central nervous system development
GO:0008289 TAS lipid binding
GO:0015267 TAS channel activity
GO:0016020 IEA membrane
GO:0016324 TAS apical plasma membrane
GO:0016505 NAS peptidase activator activity involved in apoptotic process
GO:0019898 IEA extrinsic component of membrane
GO:0019911 IDA structural constituent of myelin sheath
GO:0030154 TAS cell differentiation
GO:0042552 TAS myelination
GO:0045121 IDA membrane raft
GO:0045176 TAS apical protein localization
GO:0055085 TAS transmembrane transport
GO:1902043 IEA positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030094 mal mal, T-cell differentiation protein protein_coding Danio_rerio
ENSDARG00000043442 MAL (2 of 3) mal, T-cell differentiation protein protein_coding Danio_rerio
ENSDARG00000070401 MAL (3 of 3) mal, T-cell differentiation protein protein_coding Danio_rerio
ENSMUSG00000027375 Mal myelin and lymphocyte protein, T cell differentiation protein protein_coding Mus_musculus

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