C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon stimulated exonuclease gene 20kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172183 ISG20 9606 + 15:88636153-88656483 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306072 ISG20-001 88638743-88656483 protein_coding
  ENST00000379224 ISG20-008 88638941-88650386 protein_coding
  ENST00000546338 ISG20-007 88652036-88655625 retained_intron
  ENST00000557824 ISG20-002 88646912-88655649 retained_intron
  ENST00000558236 ISG20-011 88647820-88652186 processed_transcript
  ENST00000558942 ISG20-003 88638963-88655616 retained_intron
  ENST00000558992 ISG20-010 88636170-88637428 processed_transcript
  ENST00000559876 ISG20-006 88638953-88655511 protein_coding
  ENST00000560573 ISG20-004 88639043-88655648 retained_intron
  ENST00000560741 ISG20-009 88636153-88655621 protein_coding
  ENST00000560746 ISG20-005 88650253-88655650 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306072ENST00000379224ENST00000546338ENST00000557824ENST00000558942ENST00000559876ENST00000560573ENST00000560741
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306072 N/A N/A N/A 0.099±0.00 N/A N/A 0.127±0.00 N/A 0.188±0.00 N/A N/A 0.605±0.30 0.945±0.37 0.718±0.00
ENST00000379224 N/A N/A 0.134±0.00 N/A 5.196±0.00 5.988±0.00 N/A N/A N/A N/A N/A 1.983±0.00 N/A N/A
ENST00000546338 N/A N/A N/A N/A N/A N/A 0.813±0.00 2.195±0.00 N/A 54.661±0.00 1.577±0.00 N/A N/A N/A
ENST00000557824 N/A 2.215±0.00 N/A 0.185±0.10 0.394±0.13 0.381±0.00 0.054±0.00 0.143±0.00 0.072±0.00 N/A N/A 0.426±0.24 N/A 0.130±0.00
ENST00000558942 N/A N/A N/A 0.070±0.00 N/A N/A N/A N/A 0.208±0.00 N/A N/A N/A N/A N/A
ENST00000559876 31.346±0.00 36.480±0.00 N/A 2.846±0.00 4.826±0.00 14.429±0.00 0.987±0.00 1.589±0.74 2.890±0.00 67.616±64.79 2.008±0.00 7.887±4.46 3.950±0.00 3.424±0.11
ENST00000560573 N/A 3.080±0.00 N/A N/A N/A N/A N/A 0.136±0.00 N/A N/A N/A N/A N/A N/A
ENST00000560741 16.537±0.00 N/A N/A 0.639±0.27 3.216±0.35 4.851±1.88 0.387±0.04 N/A 1.378±0.46 3.337±0.00 1.276±0.00 11.312±7.81 8.542±4.36 3.944±1.38

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00011F CIL_00011F_0001 CGP 15:88621296-88656483
CIL_00011K CIL_00011K_0001 CGP 15:88636153-88875354

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 IDA 3'-5'-exoribonuclease activity
GO:0000738 IDA DNA catabolic process, exonucleolytic
GO:0003676 IEA nucleic acid binding
GO:0004527 IMP:IEA exonuclease activity
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006364 IEA rRNA processing
GO:0006401 IDA RNA catabolic process
GO:0008283 TAS cell proliferation
GO:0008310 IDA single-stranded DNA 3'-5' exodeoxyribonuclease activity
GO:0008859 IEA exoribonuclease II activity
GO:0009615 IDA response to virus
GO:0015030 IDA Cajal body
GO:0016605 IDA PML body
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030619 IDA U1 snRNA binding
GO:0030620 IDA U2 snRNA binding
GO:0034511 IDA U3 snoRNA binding
GO:0045071 IMP negative regulation of viral genome replication
GO:0046872 IEA metal ion binding
GO:0051607 IMP defense response to virus
GO:0060337 TAS type I interferon signaling pathway
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000039236 Isg20 interferon-stimulated protein protein_coding Mus_musculus

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