C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CCAAT/enhancer binding protein (C/EBP), beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172216 CEBPB 9606 + 20:50190734-50192689 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000303004 CEBPB-001 50190734-50192689 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000303004
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000303004 70.605±0.00 28.999±0.00 0.986±0.00 5.975±0.00 52.426±0.00 38.960±0.00 34.205±22.73 42.899±37.75 99.147±92.55 114.923±103.82 51.478±32.17 136.782±8.23 8.920±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087E CIL_00087E_0001 VISTA 20:49719805-50323644
CIL_0007ZW CIL_0007ZW_0001 VISTA 20:50090256-50696209
CIL_0007H0 CIL_0007H0_0001 CGP 20:50118254-50192689
CIL_0007H3 CIL_0007H3_0001 CGP 20:50190734-50585241

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000779 IEA condensed chromosome, centromeric region
GO:0000790 IEA nuclear chromatin
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001892 IEA embryonic placenta development
GO:0003677 TAS DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 NAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 ISS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006355 IDA:IEA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006953 TAS acute-phase response
GO:0006954 TAS inflammatory response
GO:0006955 TAS immune response
GO:0008134 IEA transcription factor binding
GO:0016363 IEA nuclear matrix
GO:0030182 IEA neuron differentiation
GO:0032496 IEA response to lipopolysaccharide
GO:0033598 IEA mammary gland epithelial cell proliferation
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0035259 IEA glucocorticoid receptor binding
GO:0042803 IEA protein homodimerization activity
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0045408 IEA regulation of interleukin-6 biosynthetic process
GO:0045444 IEA fat cell differentiation
GO:0045600 ISS positive regulation of fat cell differentiation
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0050873 IEA brown fat cell differentiation
GO:0060644 IEA mammary gland epithelial cell differentiation
GO:0060850 ISS regulation of transcription involved in cell fate commitment
GO:0071230 IEA cellular response to amino acid stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042725 cebpb CCAAT/enhancer binding protein (C/EBP), beta protein_coding Danio_rerio
ENSMUSG00000056501 Cebpb CCAAT/enhancer binding protein (C/EBP), beta protein_coding Mus_musculus

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