C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: C-type lectin domain family 7, member A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172243 CLEC7A 9606 - 12:10116777-10130258 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000298523 CLEC7A-012 10117862-10130153 protein_coding
  ENST00000304084 CLEC7A-013 10118227-10130237 protein_coding
  ENST00000310002 CLEC7A-003 10127327-10130189 protein_coding
  ENST00000349926 CLEC7A-008 10118458-10130082 nonsense_mediated_decay
  ENST00000353231 CLEC7A-001 10116777-10130241 protein_coding
  ENST00000396484 CLEC7A-004 10118068-10130185 protein_coding
  ENST00000465100 CLEC7A-002 10118458-10130082 nonsense_mediated_decay
  ENST00000525605 CLEC7A-014 10127446-10130257 protein_coding
  ENST00000528799 CLEC7A-011 10124746-10130183 retained_intron
  ENST00000529761 CLEC7A-007 10116777-10130258 nonsense_mediated_decay
  ENST00000531192 CLEC7A-006 10118549-10130257 nonsense_mediated_decay
  ENST00000533022 CLEC7A-009 10118458-10130082 protein_coding
  ENST00000534609 CLEC7A-005 10116777-10130257 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000298523ENST00000304084ENST00000310002ENST00000353231ENST00000396484ENST00000528799ENST00000534609
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000298523 1.849±0.00 N/A N/A 0.656±0.15 1.508±0.00 0.745±0.00 N/A 2.380±0.00 N/A N/A 0.025±0.00 0.540±0.00 N/A N/A
ENST00000304084 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.213±0.00 N/A N/A N/A N/A
ENST00000310002 N/A N/A N/A N/A 4.803±0.00 N/A N/A N/A N/A N/A N/A N/A 3.683±0.00 N/A
ENST00000353231 1.049±0.00 2.009±0.00 0.105±0.00 N/A 1.337±0.00 0.191±0.00 0.374±0.00 1.272±0.00 0.639±0.00 2.193±0.13 0.056±0.02 0.487±0.22 1.630±0.52 0.754±0.00
ENST00000396484 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.904±0.06 N/A N/A
ENST00000528799 N/A N/A 0.459±0.00 N/A 1.894±0.00 1.455±0.00 N/A N/A N/A 4.500±0.00 N/A N/A N/A N/A
ENST00000534609 0.625±0.00 N/A 0.073±0.00 0.380±0.00 N/A 0.840±0.00 N/A N/A 0.059±0.00 3.320±0.00 N/A 0.216±0.01 N/A 0.215±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000TC CIL_0000TC_0001 CGP 12:10069554-10130258
CIL_0000T7 CIL_0000T7_0001 CGP 12:10116777-10172138

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002221 IDA pattern recognition receptor signaling pathway
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006910 IDA phagocytosis, recognition
GO:0006954 IEA inflammatory response
GO:0008037 IDA cell recognition
GO:0008329 IDA signaling pattern recognition receptor activity
GO:0009756 TAS carbohydrate mediated signaling
GO:0016021 TAS integral component of membrane
GO:0030246 IDA carbohydrate binding
GO:0042110 TAS T cell activation
GO:0042287 NAS MHC protein binding
GO:0042832 NAS defense response to protozoan
GO:0045087 IEA innate immune response
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000079293 Clec7a C-type lectin domain family 7, member a protein_coding Mus_musculus
ENSMUSG00000102040 Clec7a C-type lectin domain family 7, member a protein_coding Mus_musculus

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