C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MACRO domain containing 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172264 MACROD2 9606 + 20:13995369-16053197 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000217246 MACROD2-010 13995369-16053197 protein_coding
  ENST00000378058 MACROD2-201 15862743-16053197 protein_coding
  ENST00000402914 MACROD2-011 15196858-16053197 protein_coding
  ENST00000407045 MACROD2-012 15985788-16050069 protein_coding
  ENST00000462552 MACROD2-004 13995681-14053679 processed_transcript
  ENST00000463861 MACROD2-002 14493479-14888668 processed_transcript
  ENST00000464883 MACROD2-009 14523391-14895581 processed_transcript
  ENST00000477147 MACROD2-001 13995495-14494087 processed_transcript
  ENST00000483997 MACROD2-006 13995502-14053679 processed_transcript
  ENST00000486914 MACROD2-013 15933276-16044592 processed_transcript
  ENST00000490428 MACROD2-005 13995773-14685079 processed_transcript
  ENST00000492055 MACROD2-008 13995503-14051860 processed_transcript
  ENST00000494602 MACROD2-003 13995737-14566933 processed_transcript
  ENST00000497992 MACROD2-007 14523398-14850506 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000217246ENST00000378058ENST00000402914ENST00000407045ENST00000463861ENST00000464883ENST00000477147ENST00000483997ENST00000486914ENST00000490428ENST00000492055ENST00000494602ENST00000497992
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000217246 N/A 0.362±0.00 N/A N/A 0.442±0.00 0.103±0.00 0.133±0.00 N/A N/A 0.421±0.18 N/A N/A 0.149±0.00 1.621±0.46
ENST00000378058 0.135±0.00 0.179±0.00 N/A 1.971±0.00 0.180±0.00 0.187±0.00 0.050±0.00 N/A N/A N/A N/A 0.241±0.00 0.456±0.00 2.153±0.00
ENST00000402914 N/A N/A 0.140±0.00 1.333±0.00 0.268±0.00 0.181±0.00 N/A N/A N/A 1.339±0.14 N/A 0.242±0.22 0.115±0.04 N/A
ENST00000407045 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.082±0.00 N/A N/A
ENST00000463861 N/A N/A N/A N/A N/A N/A N/A N/A 1.059±0.00 N/A N/A N/A N/A N/A
ENST00000464883 0.109±0.00 0.203±0.00 0.327±0.00 N/A N/A N/A 0.151±0.09 N/A 0.322±0.00 N/A N/A 0.236±0.00 N/A N/A
ENST00000477147 N/A N/A N/A 1.276±0.00 0.902±0.00 N/A 0.316±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000483997 N/A N/A N/A 1.191±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000486914 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.878±0.00 N/A
ENST00000490428 N/A N/A N/A N/A N/A 1.822±0.00 N/A 2.131±0.00 N/A N/A 2.049±0.00 N/A 0.110±0.00 N/A
ENST00000492055 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.678±0.00 0.288±0.00 N/A N/A
ENST00000494602 N/A N/A N/A N/A N/A N/A N/A 1.112±0.00 N/A N/A N/A N/A N/A N/A
ENST00000497992 N/A N/A 0.953±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002DD CIL_0002DD_0001 CGP 20:13784950-13996443
CIL_0002DE CIL_0002DE_0001 CGP 20:13849247-16053197
CIL_0002DF CIL_0002DF_0001 CGP 20:13995369-16053197

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005634 IDA nucleus
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0007420 IEA brain development
GO:0016798 IDA hydrolase activity, acting on glycosyl bonds
GO:0019213 IDA deacetylase activity
GO:0042278 IDA purine nucleoside metabolic process
GO:0051725 IDA protein de-ADP-ribosylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029609 macrod1 MACRO domain containing 1 protein_coding Danio_rerio
ENSMUSG00000068205 Macrod2 MACRO domain containing 2 protein_coding Mus_musculus

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