C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanine nucleotide binding protein (G protein), beta polypeptide 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172354 GNB2 9606 + 7:100673531-100679174 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000303210 GNB2-001 100673531-100679174 protein_coding
  ENST00000393924 GNB2-007 100676138-100679174 protein_coding
  ENST00000393926 GNB2-006 100675286-100679174 protein_coding
  ENST00000412215 GNB2-011 100676121-100677777 protein_coding
  ENST00000419828 GNB2-004 100673823-100679165 protein_coding
  ENST00000424361 GNB2-003 100673749-100679138 protein_coding
  ENST00000427895 GNB2-005 100673878-100679145 protein_coding
  ENST00000431068 GNB2-010 100675727-100678297 protein_coding
  ENST00000436220 GNB2-002 100673745-100679148 protein_coding
  ENST00000451587 GNB2-009 100673567-100678452 protein_coding
  ENST00000469287 GNB2-008 100676836-100679167 retained_intron
  ENST00000470354 GNB2-013 100677370-100678810 retained_intron
  ENST00000480159 GNB2-012 100676223-100677534 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000393924ENST00000412215ENST00000419828ENST00000424361ENST00000427895ENST00000451587ENST00000469287ENST00000470354
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000393924 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.261±0.00 N/A 91.037±7.66 77.422±19.50 32.226±0.00
ENST00000412215 N/A N/A N/A 2.508±0.00 N/A N/A 1.095±0.00 N/A N/A N/A N/A 7.569±0.00 N/A N/A
ENST00000419828 N/A 23.226±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 101.318±0.00 N/A N/A
ENST00000424361 N/A 32.436±0.00 N/A N/A 27.813±0.00 30.591±0.00 11.053±0.00 30.458±0.00 10.858±9.39 67.449±0.00 N/A N/A N/A 21.370±0.00
ENST00000427895 132.203±0.00 54.988±0.00 N/A 35.012±0.00 31.459±29.96 44.131±0.00 34.131±0.00 28.257±25.98 47.182±0.00 65.907±64.17 39.815±37.89 107.239±0.00 138.536±14.87 65.716±0.00
ENST00000451587 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 37.091±0.00 N/A 16.733±0.00 N/A
ENST00000469287 N/A N/A 0.272±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000470354 N/A N/A 2.857±0.00 20.026±16.15 3.096±0.00 17.129±14.31 0.743±0.00 N/A 2.751±0.00 6.504±0.00 5.625±0.00 48.632±41.18 62.126±0.00 30.343±3.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 TAS GTPase activity
GO:0004871 IEA signal transducer activity
GO:0005246 IEA calcium channel regulator activity
GO:0005515 IPI:IEA protein binding
GO:0005615 IDA extracellular space
GO:0005765 IDA lysosomal membrane
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006112 TAS energy reserve metabolic process
GO:0006184 TAS GTP catabolic process
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0016020 IDA membrane
GO:0031982 IDA vesicle
GO:0032403 IDA protein complex binding
GO:0043234 IEA protein complex
GO:0044281 TAS small molecule metabolic process
GO:0044297 IEA cell body
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051020 IPI GTPase binding
GO:0070062 IDA extracellular vesicular exosome
GO:0071377 TAS cellular response to glucagon stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035357 gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 protein_coding Danio_rerio
ENSMUSG00000029713 Gnb2 guanine nucleotide binding protein (G protein), beta 2 protein_coding Mus_musculus

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