C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 7, subfamily B, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172817 CYP7B1 9606 - 8:64587763-64798761 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310193 CYP7B1-001 64596135-64798761 protein_coding
  ENST00000523954 CYP7B1-002 64587763-64615814 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310193ENST00000523954
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310193 1.084±0.00 1.006±0.00 0.549±0.00 0.897±0.17 0.331±0.00 1.297±0.00 0.681±0.05 2.517±0.00 0.244±0.00 0.266±0.14 0.163±0.04 0.919±0.42
ENST00000523954 N/A N/A N/A 1.144±0.55 N/A 1.391±0.00 1.739±0.00 N/A N/A 0.686±0.26 0.776±0.38 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007NS CIL_0007NS_0002 UCNEbase 8:63773910-64847207
CIL_0008AX CIL_0008AX_0001 VISTA 8:64284007-64885029
CIL_0008IQ CIL_0008IQ_0001 VISTA 8:64571742-65172902
CIL_00031Q CIL_00031Q_0001 CGP 8:64580367-64798761
CIL_0003G9 CIL_0003G9_0001 CGP 8:64587763-65634217

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006699 IEA bile acid biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008203 IEA cholesterol metabolic process
GO:0008206 TAS bile acid metabolic process
GO:0008219 IEA cell death
GO:0008396 IEA oxysterol 7-alpha-hydroxylase activity
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IEA heme binding
GO:0033147 IEA negative regulation of intracellular estrogen receptor signaling pathway
GO:0033783 IEA 25-hydroxycholesterol 7alpha-hydroxylase activity
GO:0044281 TAS small molecule metabolic process
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0055114 IEA oxidation-reduction process
GO:0060740 IEA prostate gland epithelium morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008858 cyp7c1 cytochrome P450, family 7, subfamily C, polypeptide 1 protein_coding Danio_rerio
ENSMUSG00000039519 Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1 protein_coding Mus_musculus

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