C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 7-dehydrocholesterol reductase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172893 DHCR7 9606 - 11:71428193-71452868 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355527 DHCR7-001 71434414-71448435 protein_coding
  ENST00000407721 DHCR7-003 71434414-71448393 protein_coding
  ENST00000525137 DHCR7-013 71435308-71439076 protein_coding
  ENST00000525346 DHCR7-010 71443993-71448344 protein_coding
  ENST00000526780 DHCR7-011 71441360-71448078 protein_coding
  ENST00000527316 DHCR7-006 71437903-71448387 protein_coding
  ENST00000527452 DHCR7-005 71444041-71452868 protein_coding
  ENST00000529990 DHCR7-008 71444034-71448365 protein_coding
  ENST00000531364 DHCR7-009 71443997-71448356 protein_coding
  ENST00000533800 DHCR7-014 71434965-71438959 protein_coding
  ENST00000534701 DHCR7-012 71438749-71441347 retained_intron
  ENST00000534795 DHCR7-004 71428193-71439065 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355527ENST00000407721ENST00000526780ENST00000527316ENST00000527452ENST00000531364ENST00000533800ENST00000534701
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355527 8.742±0.00 9.791±0.00 0.757±0.00 14.699±12.41 9.086±6.99 4.696±2.29 9.502±0.00 11.164±3.34 20.481±19.64 N/A 5.126±0.00 30.602±33.08 6.170±1.79 17.886±7.81
ENST00000407721 N/A N/A N/A 0.576±0.00 N/A N/A 0.740±0.00 N/A 41.440±0.00 4.449±3.96 0.941±0.00 2.686±0.00 N/A N/A
ENST00000526780 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.758±0.00 N/A N/A
ENST00000527316 N/A N/A N/A 20.652±0.00 2.076±0.00 N/A N/A N/A N/A N/A 3.433±0.00 N/A N/A N/A
ENST00000527452 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.547±0.00 N/A N/A N/A N/A
ENST00000531364 11.894±0.00 N/A N/A 30.718±0.00 17.337±0.00 6.877±0.00 N/A N/A 0.684±0.00 N/A N/A N/A N/A 23.343±0.00
ENST00000533800 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.350±0.00 N/A 1.378±0.00 N/A N/A
ENST00000534701 N/A N/A N/A N/A N/A N/A 0.775±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001SL CIL_0001SL_0002 CGP 11:71428193-71524107

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001568 IEA blood vessel development
GO:0005640 IDA nuclear outer membrane
GO:0005783 IDA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006695 IEA cholesterol biosynthetic process
GO:0009791 IEA post-embryonic development
GO:0016020 IDA:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016126 IEA sterol biosynthetic process
GO:0016628 IEA oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0030154 IEA cell differentiation
GO:0030324 IEA lung development
GO:0035264 IEA multicellular organism growth
GO:0042127 IEA regulation of cell proliferation
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0045540 IEA regulation of cholesterol biosynthetic process
GO:0047598 IDA 7-dehydrocholesterol reductase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015564 dhcr7 7-dehydrocholesterol reductase protein_coding Danio_rerio
ENSMUSG00000058454 Dhcr7 7-dehydrocholesterol reductase protein_coding Mus_musculus

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