C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PHD finger protein 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172943 PHF8 9606 - X:53936676-54048958 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322659 PHF8-002 53943256-54043194 protein_coding
  ENST00000338154 PHF8-003 53936676-54044174 protein_coding
  ENST00000338946 PHF8-201 53936682-54044174 protein_coding
  ENST00000357988 PHF8-001 53936676-54045249 protein_coding
  ENST00000396282 PHF8-007 53937498-54022262 protein_coding
  ENST00000413386 PHF8-008 53992794-54011203 nonsense_mediated_decay
  ENST00000415025 PHF8-004 54017771-54044062 protein_coding
  ENST00000425862 PHF8-014 54017737-54042986 protein_coding
  ENST00000433120 PHF8-013 54022259-54042990 protein_coding
  ENST00000437224 PHF8-011 54017770-54048958 protein_coding
  ENST00000443302 PHF8-006 53942618-54014449 protein_coding
  ENST00000445025 PHF8-012 54022259-54043147 protein_coding
  ENST00000448003 PHF8-016 53992802-54002670 protein_coding
  ENST00000453905 PHF8-010 54017779-54048935 protein_coding
  ENST00000462182 PHF8-005 54039630-54042716 processed_transcript
  ENST00000470103 PHF8-017 53940369-53944564 retained_intron
  ENST00000490635 PHF8-015 53999487-54014493 retained_intron
  ENST00000494928 PHF8-009 53987787-53993009 retained_intron
  ENST00000615775 PHF8-202 53942617-54014451 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000322659ENST00000338154ENST00000338946ENST00000357988ENST00000396282ENST00000443302
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000322659 N/A N/A N/A N/A N/A N/A 0.366±0.00 N/A N/A 0.774±0.00 N/A N/A N/A N/A
ENST00000338154 1.958±0.00 2.994±0.00 N/A 0.655±0.00 N/A 0.997±0.00 1.008±0.92 2.205±0.00 5.419±0.00 1.575±0.99 0.387±0.00 3.601±1.05 1.659±0.12 11.147±2.93
ENST00000338946 2.257±0.00 N/A 0.534±0.00 0.288±0.00 0.920±0.00 1.122±0.00 0.292±0.00 N/A N/A N/A 0.496±0.00 3.513±0.73 2.293±0.46 17.535±1.09
ENST00000357988 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.372±0.00 N/A N/A
ENST00000396282 N/A N/A N/A 0.537±0.00 N/A 0.627±0.00 N/A 1.741±0.00 N/A N/A N/A N/A 2.633±0.00 16.484±0.00
ENST00000443302 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 16.428±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0003682 IDA chromatin binding
GO:0005506 IDA iron ion binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IDA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0007420 ISS brain development
GO:0008270 IEA:IDA zinc ion binding
GO:0015630 IDA microtubule cytoskeleton
GO:0016706 IDA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032452 IDA histone demethylase activity
GO:0032454 IDA histone demethylase activity (H3-K9 specific)
GO:0033169 IDA histone H3-K9 demethylation
GO:0035064 IDA methylated histone binding
GO:0035574 IDA histone H4-K20 demethylation
GO:0035575 IDA histone demethylase activity (H4-K20 specific)
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045943 IDA positive regulation of transcription from RNA polymerase I promoter
GO:0051864 IDA histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0061188 IDA negative regulation of chromatin silencing at rDNA
GO:0070544 IDA histone H3-K36 demethylation
GO:0071557 IDA histone H3-K27 demethylation
GO:0071558 IDA histone demethylase activity (H3-K27 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006584 phf8 PHD finger protein 8 protein_coding Danio_rerio
ENSMUSG00000023350 4921501E09Rik RIKEN cDNA 4921501E09 gene protein_coding Mus_musculus
ENSMUSG00000041229 Phf8 PHD finger protein 8 protein_coding Mus_musculus

Loading