C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: estrogen-related receptor alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173153 ESRRA 9606 + 11:64305572-64316743 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000000442 ESRRA-002 64305578-64316738 protein_coding
  ENST00000405666 ESRRA-003 64306227-64316743 protein_coding
  ENST00000406310 ESRRA-001 64305572-64316738 protein_coding
  ENST00000467987 ESRRA-005 64313771-64315890 retained_intron
  ENST00000468670 ESRRA-004 64306446-64307508 protein_coding
  ENST00000539594 ESRRA-007 64305580-64315173 protein_coding
  ENST00000545035 ESRRA-006 64314284-64316029 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMusclePlacentaENST00000000442ENST00000405666ENST00000406310
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Placenta
ENST00000000442 N/A N/A 3.025±0.00 6.471±0.00 N/A 23.447±0.00 2.109±0.00 1.197±0.00 6.314±0.00 16.783±4.24
ENST00000405666 N/A N/A N/A N/A N/A N/A N/A N/A 3.025±0.00 N/A
ENST00000406310 1.850±0.00 2.046±0.00 N/A N/A 4.999±0.00 14.612±11.14 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 TAS DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 TAS ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005496 IEA steroid binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IDA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IMP:IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0008270 IEA zinc ion binding
GO:0010467 TAS gene expression
GO:0015630 IDA microtubule cytoskeleton
GO:0019904 IPI protein domain specific binding
GO:0030278 IEA regulation of ossification
GO:0030522 TAS intracellular receptor signaling pathway
GO:0042127 IEA regulation of cell proliferation
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IDA:IEA sequence-specific DNA binding
GO:0045171 IDA intercellular bridge
GO:0045667 IEA regulation of osteoblast differentiation
GO:0045670 IEA regulation of osteoclast differentiation
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0051216 IEA cartilage development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069266 esrra estrogen-related receptor alpha protein_coding Danio_rerio
ENSMUSG00000024955 Esrra estrogen related receptor, alpha protein_coding Mus_musculus

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