C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenylate cyclase 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173175 ADCY5 9606 - 3:123282296-123449758 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309879 ADCY5-003 123284578-123416342 protein_coding
  ENST00000462833 ADCY5-001 123282296-123449758 protein_coding
  ENST00000466617 ADCY5-004 123300220-123404561 protein_coding
  ENST00000468683 ADCY5-008 123300251-123318152 retained_intron
  ENST00000470367 ADCY5-006 123352450-123419209 processed_transcript
  ENST00000474577 ADCY5-010 123297257-123304079 retained_intron
  ENST00000476455 ADCY5-007 123332595-123404283 nonsense_mediated_decay
  ENST00000478092 ADCY5-011 123284446-123287111 retained_intron
  ENST00000483566 ADCY5-005 123330940-123420274 protein_coding
  ENST00000491190 ADCY5-002 123283944-123419209 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000309879ENST00000462833ENST00000466617ENST00000468683ENST00000491190
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000309879 N/A N/A 0.289±0.00 2.839±0.00 5.718±0.00 0.852±0.00 14.754±8.21 2.316±0.00 0.478±0.00 0.320±0.00 N/A 3.599±3.36 2.140±0.99 N/A
ENST00000462833 2.704±0.00 4.610±0.00 N/A 5.858±4.45 3.370±2.76 7.256±0.00 16.645±14.53 1.586±1.43 0.854±0.66 1.702±0.00 0.431±0.00 2.920±3.59 1.931±0.94 4.173±2.09
ENST00000466617 N/A N/A N/A N/A N/A 0.904±0.00 N/A 1.520±0.00 N/A N/A N/A N/A N/A N/A
ENST00000468683 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.320±0.00 N/A N/A N/A
ENST00000491190 1.153±0.00 N/A N/A N/A N/A N/A N/A N/A 0.704±0.00 N/A N/A N/A 0.601±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00007A CIL_00007A_0002 CGP 3:123201927-123449758
CIL_000075 CIL_000075_0002 CGP 3:123282296-123585185

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001973 IEA adenosine receptor signaling pathway
GO:0004016 IEA adenylate cyclase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 ISS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006171 IEA cAMP biosynthetic process
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007189 TAS adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007191 IEA adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007195 IEA adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007268 TAS synaptic transmission
GO:0007626 IEA locomotory behavior
GO:0008179 ISS adenylate cyclase binding
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009190 IEA cyclic nucleotide biosynthetic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016849 IEA phosphorus-oxygen lyase activity
GO:0034199 TAS activation of protein kinase A activity
GO:0035556 IEA intracellular signal transduction
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0046982 ISS protein heterodimerization activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050885 IEA neuromuscular process controlling balance
GO:0055085 TAS transmembrane transport
GO:0071377 TAS cellular response to glucagon stimulus
GO:0072372 ISS primary cilium

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073795 CABZ01111926.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000087748 CABZ01112027.1 adenylate cyclase 5 protein_coding Danio_rerio
ENSDARG00000091342 adcy5 adenylate cyclase 5 protein_coding Danio_rerio
ENSMUSG00000022840 Adcy5 adenylate cyclase 5 protein_coding Mus_musculus

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