C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutaredoxin (thioltransferase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173221 GLRX 9606 - 5:95751319-95823005 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000237858 GLRX-001 95813849-95823005 protein_coding
  ENST00000379979 GLRX-002 95813971-95822714 protein_coding
  ENST00000505427 GLRX-004 95814563-95822722 protein_coding
  ENST00000507412 GLRX-003 95813979-95819502 retained_intron
  ENST00000507605 GLRX-006 95781336-95822291 processed_transcript
  ENST00000508780 GLRX-007 95751319-95822726 protein_coding
  ENST00000512469 GLRX-005 95816410-95822711 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000237858ENST00000379979ENST00000507412ENST00000507605ENST00000512469
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000237858 17.688±0.00 8.277±0.00 4.332±0.00 8.140±4.13 10.474±7.27 7.046±2.88 14.576±10.99 33.643±23.53 15.033±13.19 10.908±7.99 44.396±35.76 7.154±3.82 68.945±16.34 3.582±2.49
ENST00000379979 N/A 4.499±0.00 N/A 2.358±0.70 3.278±2.19 2.715±0.00 N/A 17.103±0.00 2.672±2.04 2.104±0.00 1.752±0.00 3.605±2.07 13.206±6.69 N/A
ENST00000507412 2.026±0.00 1.404±0.00 1.936±0.00 0.681±0.30 1.546±0.10 0.850±0.00 0.305±0.00 2.118±0.00 0.284±0.00 2.419±0.03 N/A 1.730±1.05 N/A 0.183±0.00
ENST00000507605 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.360±0.00
ENST00000512469 N/A N/A 5.467±0.00 13.432±0.00 N/A N/A 27.044±0.00 N/A 37.195±0.00 29.395±0.00 118.782±0.00 N/A 24.535±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0009055 IEA electron carrier activity
GO:0015035 IEA protein disulfide oxidoreductase activity
GO:0015038 TAS glutathione disulfide oxidoreductase activity
GO:0015949 TAS nucleobase-containing small molecule interconversion
GO:0044281 TAS small molecule metabolic process
GO:0045454 IEA cell redox homeostasis
GO:0045838 IDA positive regulation of membrane potential
GO:0047485 IPI protein N-terminus binding
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:0080058 TAS protein deglutathionylation
GO:0097573 TAS glutathione oxidoreductase activity
GO:2000651 IDA positive regulation of sodium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028106 glrx glutaredoxin (thioltransferase) protein_coding Danio_rerio
ENSMUSG00000021591 Glrx glutaredoxin protein_coding Mus_musculus

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