C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulinoma-associated 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173404 INSM1 9606 + 20:20368121-20370949 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310227 INSM1-001 20368121-20370949 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLungOvaryTestisENST00000310227
Transcript ID Adrenal Brain Breast Colon Heart Kidney Lung Ovary Testis
ENST00000310227 0.026±0.00 0.709±0.47 0.043±0.00 0.289±0.19 0.009±0.00 0.009±0.00 0.136±0.08 0.069±0.04 0.838±0.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003Q7 CIL_0003Q7_0001 CGP 20:20052514-20370949
CIL_0007R6 CIL_0007R6_0001 VISTA 20:20192309-20793556
CIL_0001TW CIL_0001TW_0001 CGP 20:20368121-20712488

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001047 IDA core promoter binding
GO:0001933 IDA negative regulation of protein phosphorylation
GO:0003309 ISS type B pancreatic cell differentiation
GO:0003310 ISS pancreatic A cell differentiation
GO:0003323 IEA type B pancreatic cell development
GO:0003358 ISS noradrenergic neuron development
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007049 IEA cell cycle
GO:0008285 IDA negative regulation of cell proliferation
GO:0010468 ISS regulation of gene expression
GO:0017053 IDA transcriptional repressor complex
GO:0030154 IEA cell differentiation
GO:0030332 IPI cyclin binding
GO:0031018 TAS endocrine pancreas development
GO:0031490 IDA chromatin DNA binding
GO:0035270 IEA endocrine system development
GO:0042421 ISS norepinephrine biosynthetic process
GO:0042826 IPI histone deacetylase binding
GO:0043254 IDA regulation of protein complex assembly
GO:0045597 ISS positive regulation of cell differentiation
GO:0046872 IEA metal ion binding
GO:0060290 IDA transdifferentiation
GO:0061104 ISS adrenal chromaffin cell differentiation
GO:0061549 ISS sympathetic ganglion development
GO:0071158 IDA positive regulation of cell cycle arrest
GO:2000179 ISS positive regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000068154 Insm1 insulinoma-associated 1 protein_coding Mus_musculus

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