C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: breast cancer metastasis suppressor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174744 BRMS1 9606 - 11:66337333-66345125 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000359957 BRMS1-001 66337339-66345125 protein_coding
  ENST00000425825 BRMS1-002 66337333-66345119 protein_coding
  ENST00000524699 BRMS1-008 66337339-66342121 protein_coding
  ENST00000525127 BRMS1-010 66340774-66345083 retained_intron
  ENST00000527375 BRMS1-007 66337778-66345079 nonsense_mediated_decay
  ENST00000529544 BRMS1-006 66341949-66345125 retained_intron
  ENST00000530238 BRMS1-003 66337369-66345089 retained_intron
  ENST00000530756 BRMS1-005 66338243-66344812 protein_coding
  ENST00000534617 BRMS1-009 66340774-66345079 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000359957ENST00000425825ENST00000524699ENST00000525127ENST00000527375ENST00000530238ENST00000530756
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000359957 9.654±0.00 19.518±0.00 N/A 3.190±0.91 6.650±5.48 6.921±0.00 7.277±0.00 9.401±7.54 7.954±6.63 6.236±5.86 21.467±0.00 22.839±2.03 28.668±10.74 19.148±0.95
ENST00000425825 N/A N/A 1.583±0.00 1.990±0.00 3.510±1.92 3.392±0.24 N/A N/A N/A N/A N/A 1.541±0.00 N/A N/A
ENST00000524699 7.632±0.00 10.912±0.00 N/A N/A N/A N/A 0.521±0.00 5.120±3.36 1.292±0.00 2.023±0.79 N/A 30.523±0.00 23.338±0.00 19.721±11.10
ENST00000525127 N/A N/A 0.612±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000527375 4.228±0.00 N/A N/A 3.357±0.00 N/A 4.462±0.00 N/A N/A N/A N/A 1.881±0.00 N/A N/A N/A
ENST00000530238 N/A N/A N/A 1.359±0.00 N/A N/A N/A N/A 0.326±0.00 0.538±0.00 N/A N/A N/A N/A
ENST00000530756 N/A N/A 1.652±0.00 N/A 1.359±0.00 N/A 0.511±0.00 N/A N/A N/A 0.218±0.00 2.739±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006915 IEA apoptotic process
GO:0009987 IEA cellular process
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0051059 IDA NF-kappaB binding
GO:0090312 IDA positive regulation of protein deacetylation
GO:2000210 IMP positive regulation of anoikis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000051955 brms1 breast cancer metastasis-suppressor 1 protein_coding Danio_rerio
ENSMUSG00000080268 Brms1 breast cancer metastasis-suppressor 1 protein_coding Mus_musculus

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