C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: betacellulin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174808 BTC 9606 - 4:74744759-74794686 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000395743 BTC-001 74744759-74794686 protein_coding
  ENST00000512743 BTC-003 74746379-74770156 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000395743ENST00000512743
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000395743 0.268±0.00 0.427±0.00 0.182±0.00 0.287±0.07 3.071±2.45 0.112±0.06 0.830±0.60 0.633±0.00 0.868±0.34 0.220±0.00 0.913±0.73 0.219±0.19 0.378±0.29
ENST00000512743 N/A N/A N/A N/A N/A N/A N/A N/A 0.748±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036A CIL_00036A_0001 CGP 4:74445134-74794686
CIL_0006SC CIL_0006SC_0001 CGP 4:74744759-75050115

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005154 IEA epidermal growth factor receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005886 IEA plasma membrane
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008083 IEA growth factor activity
GO:0008284 TAS positive regulation of cell proliferation
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0016021 IEA integral component of membrane
GO:0035810 IEA positive regulation of urine volume
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0043066 IEA negative regulation of apoptotic process
GO:0045087 TAS innate immune response
GO:0045597 IEA positive regulation of cell differentiation
GO:0045840 IEA positive regulation of mitosis
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0051781 IEA positive regulation of cell division

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063625 btc betacellulin, epidermal growth factor family member protein_coding Danio_rerio
ENSMUSG00000082361 Btc betacellulin, epidermal growth factor family member protein_coding Mus_musculus

Loading