C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: F-box and WD repeat domain containing 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174989 FBXW8 9606 + 12:116910956-117031148 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309909 FBXW8-002 116910956-117028636 protein_coding
  ENST00000455858 FBXW8-001 116910965-117031148 protein_coding
  ENST00000551773 FBXW8-003 116978067-116985404 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000309909ENST00000455858
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000309909 1.685±0.00 N/A 1.679±0.00 N/A N/A 0.493±0.00 N/A 0.356±0.00 2.458±0.63 4.674±1.71 3.458±0.00
ENST00000455858 0.793±0.00 1.897±0.00 1.327±0.00 0.509±0.00 0.375±0.10 0.104±0.00 0.739±0.51 0.205±0.00 0.726±0.37 1.080±0.02 1.549±0.50

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005794 IDA Golgi apparatus
GO:0007030 ISS Golgi organization
GO:0008283 IDA cell proliferation
GO:0016567 IEA protein ubiquitination
GO:0019005 IEA SCF ubiquitin ligase complex
GO:0031467 IDA Cul7-RING ubiquitin ligase complex
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050775 ISS positive regulation of dendrite morphogenesis
GO:0060712 IEA spongiotrophoblast layer development
GO:0060716 IEA labyrinthine layer blood vessel development
GO:1990393 IDA 3M complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079089 fbxw8 F-box and WD repeat domain containing 8 protein_coding Danio_rerio
ENSMUSG00000032867 Fbxw8 F-box and WD-40 domain protein 8 protein_coding Mus_musculus

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