C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-conjugating enzyme E2C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175063 UBE2C 9606 + 20:45812576-45816957 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000243893 UBE2C-005 45812658-45816957 protein_coding
  ENST00000335046 UBE2C-003 45812635-45816957 protein_coding
  ENST00000352551 UBE2C-006 45812674-45816957 protein_coding
  ENST00000356455 UBE2C-001 45812576-45816957 protein_coding
  ENST00000372568 UBE2C-004 45813006-45816957 protein_coding
  ENST00000405520 UBE2C-201 45812576-45816953 protein_coding
  ENST00000496085 UBE2C-002 45814410-45816802 processed_transcript
  ENST00000617055 UBE2C-202 45812576-45816953 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000243893ENST00000352551ENST00000356455ENST00000372568ENST00000405520ENST00000496085
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000243893 0.994±0.00 N/A 0.155±0.00 N/A N/A N/A N/A 0.694±0.58 0.135±0.00 N/A 0.432±0.00 60.688±0.00 N/A N/A
ENST00000352551 N/A N/A N/A N/A N/A N/A N/A 0.111±0.00 N/A 0.300±0.19 N/A 2.971±0.00 4.590±0.00 3.146±0.00
ENST00000356455 0.724±0.00 0.846±0.00 N/A N/A 0.630±0.04 1.085±0.28 0.438±0.00 0.155±0.00 N/A N/A N/A 31.431±35.72 23.234±4.98 8.701±3.15
ENST00000372568 N/A 0.154±0.00 N/A N/A 0.726±0.38 N/A N/A 0.092±0.00 N/A N/A N/A 0.214±0.00 N/A 1.127±0.00
ENST00000405520 N/A N/A N/A N/A N/A N/A N/A N/A 0.041±0.00 N/A N/A N/A N/A 3.348±0.00
ENST00000496085 0.408±0.00 0.618±0.00 N/A 0.266±0.19 N/A 1.051±0.00 0.289±0.00 N/A 0.094±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00002L CIL_00002L_0001 CGP 20:45791937-45816957
CIL_00002K CIL_00002K_0001 CGP 20:45812576-45833745

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005680 IDA anaphase-promoting complex
GO:0005829 TAS cytosol
GO:0006511 IDA ubiquitin-dependent protein catabolic process
GO:0007094 TAS mitotic spindle assembly checkpoint
GO:0008054 IDA cyclin catabolic process
GO:0010458 IMP exit from mitosis
GO:0010994 IDA free ubiquitin chain polymerization
GO:0016567 IDA protein ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0031145 IDA anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031536 IMP positive regulation of exit from mitosis
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051488 TAS activation of anaphase-promoting complex activity
GO:0070936 IDA protein K48-linked ubiquitination
GO:0070979 IDA protein K11-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035770 ube2c ubiquitin-conjugating enzyme E2C protein_coding Danio_rerio
ENSMUSG00000001403 Ube2c ubiquitin-conjugating enzyme E2C protein_coding Mus_musculus

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