C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lipoprotein lipase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175445 LPL 9606 + 8:19901717-19967258 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000311322 LPL-001 19938971-19967258 protein_coding
  ENST00000519773 LPL-007 19939256-19948303 nonsense_mediated_decay
  ENST00000520959 LPL-006 19901717-19954151 protein_coding
  ENST00000521994 LPL-005 19939256-19951828 processed_transcript
  ENST00000522701 LPL-004 19938933-19951836 protein_coding
  ENST00000523696 LPL-008 19939372-19948485 retained_intron
  ENST00000524029 LPL-003 19938870-19951908 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverLungOvaryPlacentaTestisENST00000311322ENST00000520959ENST00000522701
Transcript ID Brain Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000311322 0.694±0.00 60.754±20.54 N/A 23.180±0.00 22.265±0.00 0.941±0.00 4.000±0.00 0.091±0.00
ENST00000520959 N/A N/A 1.143±0.00 N/A N/A N/A N/A N/A
ENST00000522701 2.961±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003TK CIL_0003TK_0001 CGP 8:19817140-19967258
CIL_0003TS CIL_0003TS_0001 CGP 8:19901717-20183206

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0004465 ISS:IEA lipoprotein lipase activity
GO:0004620 ISS phospholipase activity
GO:0004806 ISS triglyceride lipase activity
GO:0005102 IPI receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005886 IEA plasma membrane
GO:0006629 IEA lipid metabolic process
GO:0006633 ISS fatty acid biosynthetic process
GO:0006641 ISS triglyceride metabolic process
GO:0006644 ISS phospholipid metabolic process
GO:0007603 TAS phototransduction, visible light
GO:0008201 IDA heparin binding
GO:0009409 IEA response to cold
GO:0009986 IEA cell surface
GO:0010744 IC positive regulation of macrophage derived foam cell differentiation
GO:0010886 IMP positive regulation of cholesterol storage
GO:0010890 IMP positive regulation of sequestering of triglyceride
GO:0016042 IEA lipid catabolic process
GO:0017129 IEA triglyceride binding
GO:0019432 IEA triglyceride biosynthetic process
GO:0019433 ISS triglyceride catabolic process
GO:0031012 IEA extracellular matrix
GO:0031225 IEA anchored component of membrane
GO:0034185 IPI apolipoprotein binding
GO:0034361 IEA very-low-density lipoprotein particle
GO:0034371 IC chylomicron remodeling
GO:0034372 ISS very-low-density lipoprotein particle remodeling
GO:0042157 TAS lipoprotein metabolic process
GO:0042493 IEA response to drug
GO:0042627 IEA chylomicron
GO:0044281 TAS small molecule metabolic process
GO:0052689 IEA carboxylic ester hydrolase activity
GO:0070062 IDA extracellular vesicular exosome
GO:0070328 IGI triglyceride homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087697 lpl lipoprotein lipase protein_coding Danio_rerio
ENSDARG00000091659 LPL (2 of 2) lipoprotein lipase protein_coding Danio_rerio
ENSMUSG00000015568 Lpl lipoprotein lipase protein_coding Mus_musculus

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