C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: stratifin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175793 SFN 9606 + 1:26863138-26864457 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000339276 SFN-001 26863138-26864457 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000339276
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000339276 3.110±0.00 1.067±0.00 3.503±0.00 5.864±4.43 8.993±0.84 0.052±0.03 1.692±1.64 2.202±0.00 45.338±44.65 59.678±48.17 12.492±5.84 0.494±0.37

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007T4 CIL_0007T4_0001 VISTA 1:26423129-27024414

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000079 IEA regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0001836 IDA release of cytochrome c from mitochondria
GO:0003334 IEA keratinocyte development
GO:0005515 IPI protein binding
GO:0005615 TAS extracellular space
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006469 TAS negative regulation of protein kinase activity
GO:0006915 TAS apoptotic process
GO:0007165 TAS signal transduction
GO:0008426 TAS protein kinase C inhibitor activity
GO:0008630 IDA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010482 ISS regulation of epidermal cell division
GO:0010839 IEA negative regulation of keratinocyte proliferation
GO:0019901 IEA protein kinase binding
GO:0019904 IEA protein domain specific binding
GO:0030216 IEA keratinocyte differentiation
GO:0030307 IEA positive regulation of cell growth
GO:0030659 TAS cytoplasmic vesicle membrane
GO:0031424 IEA keratinization
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043588 IEA skin development
GO:0045606 ISS positive regulation of epidermal cell differentiation
GO:0046827 IEA positive regulation of protein export from nucleus
GO:0051219 IEA phosphoprotein binding
GO:0051726 IEA regulation of cell cycle
GO:0061024 TAS membrane organization
GO:0061436 ISS establishment of skin barrier
GO:0070062 IDA extracellular vesicular exosome
GO:0071901 TAS negative regulation of protein serine/threonine kinase activity
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023323 ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b protein_coding Danio_rerio
ENSDARG00000042539 ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a protein_coding Danio_rerio
ENSMUSG00000047281 Sfn stratifin protein_coding Mus_musculus

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